CT works by activating the G-proteinsGs and Gq often found on osteoclasts, on cells in the kidney, and on cells in a number of regions of the brain.[9] It may also affect the ovaries in women and the testes in men.
The function of the CT receptor protein is modified through its interaction with Receptor activity-modifying proteins (RAMPs), forming the multimeric amylin receptors AMY1 (CT + RAMP1), AMY2 (CT + RAMP2), and AMY3 (CT+ RAMP3).[10]
^"Calcitonin Receptors: Introduction". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-12.
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Nosaka Y, Tachi Y, Shimpuku H, Kawamura T, Ohura K (2002). "Association of calcitonin receptor gene polymorphism with early marginal bone loss around endosseous implants". The International Journal of Oral & Maxillofacial Implants. 17 (1): 38–43. PMID11858573.
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"Calcitonin Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2007-07-23.