Aku may refer to:
- Aku, Nigeria, a town in Enugu State
- "Aku" (poem), 1943, by Chairil Anwar
- Aku people of Gambia
- Aku dialect, a dialect of Sierra Leone Krio
- Aku, the main antagonist of the animated television series Samurai Jack
- The Hawaiian word for skipjack tuna
- Hal Lewis (Aku), a former Hawaii radio presenter
- Aku (given name)
- Aku (album), by Japanese band MUCC (2020)
AKU may refer to:
- Aksu Airport, China (IATA code AKU)
- Aryabhatta Knowledge University, Bihar, India
- Adaptation kit upgrade, for updating Windows Mobile
- Aga Khan University, Pakistan, East Africa, and the UK.
- Al-Kafaàt University, Beirut, Lebanon
- Alkaptonuria, or black urine disease
- Algemene Kunstzijde Unie, a Dutch company merged into Akzo Nobel