Cannabis Ruderalis

thcscience_admin
Browse history interactively
← Previous edit
Content deleted Content added
VisualWikitext
No edit summary
m fixed lint errors – missing end tag
 
(29 intermediate revisions by 8 users not shown)
Line 3: Line 3:
| title = [[Cannabinoid receptor]] [[receptor modulator|modulator]]s
| title = [[Cannabinoid receptor]] [[receptor modulator|modulator]]s
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| listclass = hlist
| bodyclass = hlist
| bodyclass = hlist
| groupstyle = text-align:center;
| groupstyle = text-align:center;


| group1 = [[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligands]])</small>
| group1 = [[Receptor (biochemistry)|Receptor]]<br />{{nobold|([[Ligand (biochemistry)|ligands]])}}
| list1 = {{Navbox subgroup
| list1 = {{Navbox|subgroup
| groupstyle = text-align:center;
| groupstyle = text-align:center;
| groupwidth = 4em;


| group1 = [[Cannabinoid receptor type 1|CB<sub>1</sub>]]
| group1 = {{abbrlink|CB<sub>1</sub>|Cannabinoid receptor type 1}}
| list1 =
| list1 =
{{Navbox|child
* '''Agonists''' ''(abridged; see [[Template:Cannabinoids|here]] for more)''''':''' [[2-Arachidonoylglycerol|2-AG]]
|group1=Agonists<br>''(abridged,<br>[[Template:Cannabinoids|full list]])''
|list1=
⚫
* [[2-Arachidonoylglycerol|2-AG]]
* [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
* [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
* [[11-Hydroxy-THC]]
* [[11-Hydroxy-THC]]
* [[α-Amyrin]]
* [[Amyrin|α-Amyrin · β-Amyrin]]
⚫
* [[β-Amyrin]]
* [[AB-CHMINACA]]
* [[AB-CHMINACA]]
* [[AM-1172]]
* [[AM-1172]]
Line 36: Line 38:
* [[Epicatechin gallate|ECG]]
* [[Epicatechin gallate|ECG]]
* [[Epigallocatechin gallate|EGCG]]
* [[Epigallocatechin gallate|EGCG]]
* [[Epicatechin]]
* [[Catechin|Epicatechin]]
* [[Gallocatechol|Gallocatechol (gallocatechin)]]
* [[Gallocatechol|Gallocatechol (gallocatechin)]]
* [[Honokiol]]
* [[Honokiol]]
Line 59: Line 61:
* [[WIN 55,212-2]]
* [[WIN 55,212-2]]
* [[Yangonin]]
* [[Yangonin]]
|group2=Inverse agonists

|list2=
* '''Antagonists:''' [[AM251|AM-251]]
* [[AM-251 (drug)|AM-251]]
*[[ INV-202 ]]
⚫
* [[Rimonabant]]
⚫
* [[Surinabant]]
⚫
* [[Taranabant]]
⚫
* [[TM-38837]]
* [[Zevaquenabant]]
|group3=Antagonists
|list3=
* [[AM-6545]]
* [[AM-6545]]
* [[Cannabidiol]]
* [[Cannabidiol]]
Line 75: Line 86:
* [[PF-514273]]
* [[PF-514273]]
* [[PipISB]]
* [[PipISB]]
⚫
* [[Rimonabant]]
* [[Rosonabant]]
* [[Rosonabant]]
⚫
* [[Surinabant]]
⚫
* [[Taranabant]]
* [[Tetrahydrocannabivarin|THCV]]
* [[Tetrahydrocannabivarin|THCV]]
⚫
* [[TM-38837]]
* [[VCHSR]]
* [[VCHSR]]
* [[Virodhamine]]
* [[Virodhamine]]
}}
⚫
<!-- * '''Unknown/unsorted:''' [[Methoxy arachidonyl fluorophosphonate|MAFP]] -->


| group2 = {{abbrlink|CB<sub>2</sub>|Cannabinoid receptor type 2}}
* '''Antibodies:''' [[Brizantin|Brizantin (Бризантин)]]<!--Approved in Russia for nicotine withdrawal/smoking cessation-->
* [[Dietressa|Dietressa (Диетресса)]]<!--Approved in Russia for weight loss-->

⚫
* '''Unknown/unsorted:''' [[Methoxy arachidonyl fluorophosphonate|MAFP]]

| group2 = [[Cannabinoid receptor type 2|CB<sub>2</sub>]]
| list2 =
| list2 =
{{navbox|child
⚫
* '''Agonists:''' [[2-Arachidonoylglycerol|2-AG]]
|group1=Agonists
|list1=
* [[2-Arachidonoylglycerol|2-AG]]
* [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
* [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
* [[3,3'-Diindolylmethane]]
* [[3,3'-Diindolylmethane]]
* [[4-O-Methylhonokiol]]
* [[4-O-Methylhonokiol]]
* [[α-Amyrin]]
* [[Amyrin|α-Amyrin · β-Amyrin]]
* [[β-Amyrin]]
* [[A-796,260]]
* [[A-796,260]]
* [[A-834,735]]
* [[A-834,735]]
Line 111: Line 117:
* [[CB-13]]<!--Peripherally restricted-->
* [[CB-13]]<!--Peripherally restricted-->
* [[CBS-0550]]
* [[CBS-0550]]
* [[CP-55,940]]
* [[CP 55,940]]
* [[GW-405,833|GW-405,833 (L-768,242)]]
* [[GW-405,833|GW-405,833 (L-768,242)]]
* [[GW-842,166X]]
* [[GW-842,166X]]
Line 123: Line 129:
* [[L-759,633]]
* [[L-759,633]]
* [[L-759,656]]
* [[L-759,656]]
* [[Lenabasum|Lenabasum (anabasum)]]
* [[Magnolol]]
* [[Magnolol]]
* [[MDA-19]]
* [[MDA-19]]
* [[Nabitan]]
* [[Nabitan]]
* [[N-Arachidonoyl dopamine|NADA]]
* [[N-Arachidonoyl dopamine|NADA]]
* [[Olorinab|Olorinab (APD-371)]]
* [[PF-03550096]]
* [[PF-03550096]]
* [[S-444,823]]
* [[S-444,823]]
Line 138: Line 146:
* [[Virodhamine]]
* [[Virodhamine]]


* '''Antagonists:''' [[4-O-Methylhonokiol]]
|group2=Antagonists
|list2=
* [[4-O-Methylhonokiol]]
* [[AM-630]]
* [[AM-630]]
* [[BML-190]]
* [[BML-190]]
Line 147: Line 157:
* [[WIN 54,461]]
* [[WIN 54,461]]
* [[WIN 56,098]]
* [[WIN 56,098]]
}}

| group3 = [[NAGly receptor|{{abbr|NAGly|N-Arachidonyl glycine receptor}}<br />({{abbr|GPR18|G protein-coupled receptor 18}})]]
| group3 = [[GPR18]]
| list3 =
| list3 =
{{navbox|child|
⚫
* '''Agonists:''' [[Abnormal cannabidiol]]
|group1=Agonists
|list1=
⚫
* [[Abnormal cannabidiol]]
* [[Arachidonylcyclopropylamide|ACPA]]
* [[Arachidonylcyclopropylamide|ACPA]]
* [[AM251]]
* [[AM-251 (drug)|AM251]]
* [[Anandamide]]
* [[Anandamide]]
* [[Cannabidiol]]
* [[Cannabidiol]]
Line 159: Line 172:
* [[O-1602]]
* [[O-1602]]


* '''Antagonists:''' [[CID-85469571]]
|group2=Antagonists
|list2=
⚫
* [[PSB-CB5]]
* [[O-1918]]
* [[O-1918]]
}}

| group4 = {{abbr|[[GPR55]]|G protein-coupled receptor 55}}<!--{{abbr|[[G protein-coupled receptor 55|GPR55]]|G protein-coupled receptor 55}}-->
| group4 = [[GPR55]]
| list4 =
| list4 =
{{navbox|child|
⚫
* '''Agonists:''' [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
|group1=Agonists
|list1=
⚫
* [[2-Arachidonyl glyceryl ether|2-AGE (noladin ether)]]
* [[2-Arachidonoyl lysophosphatidylinositol|2-ALPI]]
* [[2-Arachidonoyl lysophosphatidylinositol|2-ALPI]]
* [[Abnormal cannabidiol]]
* [[Abnormal cannabidiol]]
* [[AM251|AM-251]]
* [[AM-251 (drug)|AM-251]]
* [[CID1011163]]<!--PubChem compound ID-->
* [[CID1011163]]<!--PubChem compound ID-->
* [[CID1252842]]<!--PubChem compound ID-->
* [[CID1252842]]<!--PubChem compound ID-->
Line 182: Line 200:
* [[Tetrahydrocannabinol|THC (dronabinol)]]
* [[Tetrahydrocannabinol|THC (dronabinol)]]


* '''Antagonists:''' [[Cannabidiol]]
|group2=Antagonists
|list2=
* [[Cannabidiol]]
* [[CID-16020046]]
* [[CID-16020046]]
* [[ML-191]]
* [[ML-191]]
Line 192: Line 212:
* [[PSB-SB-1203]]
* [[PSB-SB-1203]]
* [[Tetrahydromagnolol]]
* [[Tetrahydromagnolol]]
}}

| group5 = [[GPR119]]
| group5 = {{abbr|[[GPR119]]|G protein-coupled receptor 119}}
| list5 =
| list5 =
{{navbox|child|
⚫
* '''Agonists:''' [[2-Oleoylglycerol]]
group1=Agonists
|list1=
⚫
* [[2-Oleoylglycerol]]
* [[Anandamide]]
* [[Anandamide]]
* [[APD668]]
* [[APD668]]
Line 208: Line 231:


<!--* '''Antagonists:'''--> <!--None known yet.--->
<!--* '''Antagonists:'''--> <!--None known yet.--->
}}
<!-- | group6 = Unsorted
| list6 =
* '''Agonists:''' [[Revosimeline]] -->


}}
}}


| group2 = [[Endocannabinoid transporters|Transporter]]<br /><small>([[reuptake modulator|modulator]]s)</small>
| group2 = [[Endocannabinoid transporter|Transporter]]<br />{{nobold|([[reuptake modulator|modulator]]s)}}
| list2 = {{Navbox subgroup
| list2 = {{Navbox|subgroup
| groupstyle = text-align:center;
| groupstyle = text-align:center;
| groupwidth = 4em;


| group1 = [[Endocannabinoid transporter|eCBTs]]
| group1 = {{abbrlink|eCBTs|Endocannabinoid transporter}}
| list1 =
| list1 =
* '''Inhibitors:''' [[5'-DMH-CBD]]
* '''Inhibitors:''' [[5'-DMH-CBD]]
* [[AM-404]]
* [[AM404|AM-404]]
* [[AM-1172]]
* [[AM-1172]]
* [[Arachidonoyl serotonin]]
* [[Arachidonoyl serotonin]]
* [[Arvanil]]
* [[Arvanil]]
* [[Cannabidiol]]
* [[Cannabidiol]]
* [[Guineensine]]
* [[Guineesine|Guineensine]]
* [[LY-2183240]]
* [[LY-2183240]]
* [[O-2093]]
* [[O-2093]]
Line 230: Line 258:
* [[SB-FI-26]]
* [[SB-FI-26]]
* [[UCM-707]]
* [[UCM-707]]
* [[URB-597]]
* [[URB597|URB-597]]
* [[VDM-11]]
* [[VDM-11]]
* [[WOBE490]]
* [[WOBE490]]
Line 238: Line 266:
}}
}}


| group3 = [[Enzyme]]<br /><small>([[Enzyme modulator|modulator]]s)</small>
| group3 = [[Enzyme]]<br />{{nobold|([[Enzyme modulator|modulator]]s)}}
| list3 = {{Navbox subgroup
| list3 = {{Navbox|subgroup
| groupstyle = text-align:center;
| groupstyle = text-align:center;
| groupwidth = 4em;


| group1 = [[Fatty acid amide hydrolase|FAAH]]
| group1 = {{abbrlink|FAAH|Fatty acid amide hydrolase}}
| list1 =
| list1 =
* '''Inhibitors:''' [[4-Nonylphenylboronic acid]]
* '''Inhibitors:''' [[4-Nonylphenylboronic acid]]
* [[AACOCF3|AACOCF<sub>3</sub>]]<!--Non-selective-->
* [[Arachidonyl trifluoromethyl ketone|AACOCF<sub>3</sub>]]<!--Non-selective-->
* [[AM404|AM-404]]
* [[AM404|AM-404]]
* [[Arachidonoyl serotonin]]
* [[Arachidonoyl serotonin]]
Line 254: Line 283:
* [[JNJ-1661010]]
* [[JNJ-1661010]]
* [[JNJ-42165279]]
* [[JNJ-42165279]]
* [[JZL-195]]
* [[JZL195|JZL-195]]
* [[Kaempferol]]
* [[Kaempferol]]
* [[LY-2183240]]
* [[LY-2183240]]
Line 268: Line 297:
* [[TC-F 2]]
* [[TC-F 2]]
* [[UCM710]]
* [[UCM710]]
* [[URB-597]]
* [[URB597|URB-597]]


* '''Activators:''' [[PDP-EA]]
* '''Activators:''' [[PDP-EA]]
Line 278: Line 307:
* [[JJKK 048]]
* [[JJKK 048]]
* [[JW 642]]
* [[JW 642]]
* [[JZL-184]]
* [[JZL184|JZL-184]]
* [[JZL-195]]
* [[JZL195|JZL-195]]
* [[JZP-361]]
* [[JZP-361]]
* [[KML 29]]
* [[KML 29]]
* [[Methyl arachidonyl fluorophosphonate|MAFP]]<!--Non-selective-->
* [[Methoxy arachidonyl fluorophosphonate|MAFP]]<!--Non-selective-->
* [[MJN110]]
* [[MJN110]]
* [[N-Arachidonoylmaleimide|NAM]]<!--Non-selective-->
* [[N-Arachidonoylmaleimide|NAM]]<!--Non-selective-->
* [[Pristimerin]]<!--Reversible-->
* [[Pristimerin]]<!--Reversible-->
* [[URB-602]]
* [[URB602|URB-602]]


| group3 = [[ABHD6]]
| group3 = {{abbr|[[ABHD6]]|alpha/beta-Hydrolase domain containing 6}}
| list3 =
| list3 =
* '''Inhibitors:''' [[JZP-169]]
* '''Inhibitors:''' [[JZP-169]]
Line 303: Line 332:
* [[WWL-70]]
* [[WWL-70]]


| group4 = [[ABHD12]]
| group4 = {{abbr|[[ABHD12]]|alpha/beta-Hydrolase domain containing 12}}
| list4 =
| list4 =
* '''Inhibitors:''' [[Betulinic acid]]
* '''Inhibitors:''' [[Betulinic acid]]
* [[Maslinic acid]]
* [[Maslinic acid]]
* [[Methyl arachidonyl fluorophosphonate|MAFP]]<!--Non-selective-->
* [[Methoxy arachidonyl fluorophosphonate|MAFP]]<!--Non-selective-->
* [[Oleanolic acid]]
* [[Oleanolic acid]]
* [[Orlistat|Orlistat (tetrahydrolipstatin)]]<!--Non-selective-->
* [[Orlistat|Orlistat (tetrahydrolipstatin)]]<!--Non-selective-->
Line 318: Line 347:
* '''Precursors:''' [[Phosphatidylethanolamine]]
* '''Precursors:''' [[Phosphatidylethanolamine]]
* [[N-Acylphosphatidylethanolamine|NAPE]]
* [[N-Acylphosphatidylethanolamine|NAPE]]
* [[Diacylglycerol]]
* [[Diglyceride|Diacylglycerol]]


* '''Others:''' [[2-Palmitoylglycerol|2-PG]] ''(directly potentiates activity of 2-AG at CB<sub>1</sub> receptor)''
* '''Others:''' [[2-Palmitoylglycerol|2-PG]] ''(directly potentiates activity of 2-AG at CB<sub>1</sub> receptor)''
Line 324: Line 353:


| below =
| below =
;See also
⚫
* '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]] • [[Template:Cannabinoids|Cannabinoids]] (cannabinoids by structure)''
:'' [[Template:Receptor modulators|Receptor/signaling modulators]]''
⚫
:'' [[Template:Cannabinoids|Cannabinoids]] (cannabinoids by structure)''


}}<noinclude>
}}<noinclude>
{{Documentation}}
{{collapsible option}}
[[Category:Cannabinoids]]
[[Category:Drug templates by receptor, channel, or pump]]
</noinclude>
</noinclude>

Latest revision as of 08:05, 5 December 2023

source: https://en.wikipedia.org/w/index.php?title=Template:Cannabinoid_receptor_modulators&diff=1188415654&oldid=775650380

Leave a Reply