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--[[Special:Contributions/173.66.69.186|173.66.69.186]] ([[User talk:173.66.69.186|talk]]) 01:56, 26 August 2017 (UTC)
--[[Special:Contributions/173.66.69.186|173.66.69.186]] ([[User talk:173.66.69.186|talk]]) 01:56, 26 August 2017 (UTC)
:I think the 'different intermediates' portion is to emphasize the different precursors (safrole, isosafrol, etc.). The "in literature" part can be cut. [[User:Sizeofint|Sizeofint]] ([[User talk:Sizeofint|talk]]) 08:15, 26 August 2017 (UTC)
:I think the 'different intermediates' portion is to emphasize the different precursors (safrole, isosafrol, etc.). The "in literature" part can be cut. [[User:Sizeofint|Sizeofint]] ([[User talk:Sizeofint|talk]]) 08:15, 26 August 2017 (UTC)

== Provenience ==


I had this crazy idea... How come people don't tell the truth and save everyone of the troubles arising from lies. Like: Mdma is extracted from sea shells... plain and simple.
*see also cocaine (ivory)

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Semi-protected edit request on 16 March 2017

Replace citation [21] in the following sentence "Researchers are investigating whether a few low doses of MDMA may assist in treating severe, treatment-resistant posttraumatic stress disorder (PTSD).[12][21]" with this citation: Amoroso, T., & Workman, M. (2016). Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: A preliminary meta-analysis and comparison to prolonged exposure therapy. Journal of Psychopharmacology, 30(7), 595-600. 2601:18B:8200:61D8:7CB6:AB0F:5BE5:4F54 (talk) 00:12, 17 March 2017 (UTC)[reply]

 Done Sizeofint (talk) 00:31, 17 March 2017 (UTC)[reply]

Paste

The following has some useful references but I think it is redundant with current content and too loose on efficacy. Sizeofint (talk) 20:37, 18 May 2017 (UTC)[reply]

MDMA is known to improve sociability, friendliness, extroversion, to increase empathy and feelings of closeness with others, and to reduce interpersonal defensiveness.[1][2][3][4][5] These effects are relevant to people with social anxiety and a group of researchers find that MDMA has therapeutic benefits for alleviating social anxiety.[6][7][8]

Why do you think this content which is humanizing straight research is redundant?--TMCk (talk) 02:35, 19 May 2017 (UTC)[reply]
We already have a section on effects. I don't think it is necessary to repeat them in the research section. "A group of researchers find that MDMA has therapeutic benefits for alleviating social anxiety" has some weasel wording issues (which group?). Additionally, at least one of the sources was a bit more nuanced (I haven't closely examined the others yet) with the authors saying it "may" have therapeutic benefit, not that they believe it certainly does as this wording implies. Sizeofint (talk) 06:33, 19 May 2017 (UTC)[reply]
With respect to the sentence – "MDMA is known to improve sociability, friendliness, extroversion, to increase empathy and feelings of closeness with others, and to reduce interpersonal defensiveness.[1][2][3][4][5]" – WP:MEDRS sources are required since these are clinical claims of drug effects. Among the cited refs, only this ref[3] is a MEDRS-compliant source (i.e., a medical review). In any event, if others think that this is worth covering, I don't think that it should be too difficult to find other reviews that cover the effects that aren't supported by the cited review. There's plenty of medical sources which state that amphetamine increases sociability and self-expression, so MDMA is not unique in that regard. The non-empathogenic effects of MDMA on social behavior are likely derived from its amphetamine-like dopaminergic effects. Seppi333 (Insert ) 09:01, 19 May 2017 (UTC)[reply]


Section references

References

  1. ^ a b Scahill, Lawrence; Anderson, George M. (15 December 2010). "Is ecstasy an empathogen?". Biological psychiatry. 68 (12): 1082–1083. doi:10.1016/j.biopsych.2010.10.020. ISSN 0006-3223. Retrieved 18 May 2017.
  2. ^ a b Bedi, Gillinder; Hyman, David; de Wit, Harriet (15 December 2010). "Is ecstasy an 'empathogen'? Effects of MDMA on prosocial feelings and identification of emotional states in others". Biological psychiatry. 68 (12): 1134–1140. doi:10.1016/j.biopsych.2010.08.003. ISSN 0006-3223. Retrieved 18 May 2017.
  3. ^ a b c Kamilar-Britt, Philip; Bedi, Gillinder (18 May 2017). "The Prosocial Effects of 3,4-methylenedioxymethamphetamine (MDMA): Controlled Studies in Humans and Laboratory Animals". Neuroscience and biobehavioral reviews. 57: 433–446. doi:10.1016/j.neubiorev.2015.08.016. ISSN 0149-7634. Retrieved 18 May 2017.
  4. ^ a b Bedi, Gillinder; Phan, K. Luan; Angstadt, Mike; de Wit, Harriet (18 May 2017). "Effects of MDMA on sociability and neural response to social threat and social reward". Psychopharmacology. 207 (1): 73–83. doi:10.1007/s00213-009-1635-z. ISSN 0033-3158. Retrieved 18 May 2017.
  5. ^ a b "Ecstasy ingredient touted as treatment for anxiety in autism | Spectrum | Autism Research News". Spectrum | Autism Research News. 16 November 2016. Retrieved 18 May 2017.
  6. ^ Syder, Alexander. MDMA Case Study. A Case for Decriminalization or Prohibition?. GRIN Verlag. ISBN 9783668046870. Retrieved 18 May 2017.
  7. ^ Ingersoll, R. Elliott; Rak, Carl F. Psychopharmacology for Mental Health Professionals: An Integrative Approach. Cengage Learning. ISBN 9781305537231. Retrieved 18 May 2017.
  8. ^ Ph.D Vera Sonja, Maass. Understanding Social Anxiety: A Recovery Guide for Sufferers, Family, and Friends. ABC-CLIO. ISBN 9781440841965. Retrieved 18 May 2017.

"As of 2017, MDMA has no accepted medical indications."

Neither of the two provided sources actually support this weird statement. The first suggests that MDMA should be removed from its "no medical use" status and the other says that its use for therapeutic use is rare these days. --86.50.81.67 (talk) 02:41, 23 May 2017 (UTC)[reply]

If the authors are arguing its status should be changed then it currently must have no accepted medical use. Sizeofint (talk) 04:14, 23 May 2017 (UTC)[reply]
I agree with Sizeofint. The lack of medical indications logically follows from the fact that it has "no medical uses"; in any event, the source that was recently added to that sentence explicitly states this. Seppi333 (Insert ) 18:55, 23 May 2017 (UTC)[reply]

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Oddly phrased sentance.

"There are numerous methods available in the literature to synthesize MDMA via different intermediates.[98][99][100][101]" seems this sentence is worded very poorly. It's redundant, essentially stating "There are many ways to make MDA" twice. I also don't think it needs the qualifier "in literature". I think a better sentence might be "There are numerous methods available to synthesize MDMA.[98][99][100][101]"

--173.66.69.186 (talk) 01:56, 26 August 2017 (UTC)[reply]

I think the 'different intermediates' portion is to emphasize the different precursors (safrole, isosafrol, etc.). The "in literature" part can be cut. Sizeofint (talk) 08:15, 26 August 2017 (UTC)[reply]

Provenience

I had this crazy idea... How come people don't tell the truth and save everyone of the troubles arising from lies. Like: Mdma is extracted from sea shells... plain and simple.

  • see also cocaine (ivory)

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