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{{Vital article|topic=Biology|subpage=Health|level=5|class=B}}
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== External links modified ==

Hello fellow Wikipedians,

I have just modified one external link on [[MDMA]]. Please take a moment to review [[special:diff/819647088|my edit]]. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit [[User:Cyberpower678/FaQs#InternetArchiveBot|this simple FaQ]] for additional information. I made the following changes:
*Added archive https://web.archive.org/web/20150812022920/http://www.westerndailypress.co.uk/sick-dealers-peddle-Shaun-Sheep-Ecstasy-tablets/story-27521142-detail/story.html to http://www.westerndailypress.co.uk/sick-dealers-peddle-Shaun-Sheep-Ecstasy-tablets/story-27521142-detail/story.html

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== The BP in a medium vacuum should not be listed ==
Cheers.—[[User:InternetArchiveBot|'''<span style="color:darkgrey;font-family:monospace">InternetArchiveBot</span>''']] <span style="color:green;font-family:Rockwell">([[User talk:InternetArchiveBot|Report bug]])</span> 14:53, 10 January 2018 (UTC)


The infobox currently lists the boiling point at 0.4 mmHg, which is a medium vacuum. It is not sourced, and it doesn't say whether this is the free base or what salt it is. This is nearly useless information and it isn't sourced, it should simply be removed. The melting points of the free base and any common salts, at atmospheric pressure, would be interesting data to add. Boiling point in a vacuum is silly. [[Special:Contributions/209.6.225.254|209.6.225.254]] ([[User talk:209.6.225.254|talk]]) 09:36, 24 November 2023 (UTC)
== Possible source for updating this article. ==


== Is MDMA a psychedelic or not? ==
Several sentences in this article say "As of 2017 ..." and I ran across the following article which indicates that the research status of MDMA is changing. I do not understand medical terminology much so maybe some who does can use this article as appropriate.
* https://theconversation.com/is-psychiatry-ready-for-medical-mdma-94105
[[Special:Contributions/172.88.134.103|172.88.134.103]] ([[User talk:172.88.134.103|talk]]) 11:14, 31 March 2018 (UTC)
::We would need sources as outline at [[WP:MEDRS]]
::Yes MDMA is being studied but is far from approved. [[User:Doc James|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Doc James|talk]] · [[Special:Contributions/Doc James|contribs]] · [[Special:EmailUser/Doc James|email]]) 00:37, 1 April 2018 (UTC)
::: I certainly understand the need for specialized sources, but surely if the FDA altered the drug's technical designation and approved it for special clinical studies those are significant facts that should be part of the article, yes? A quick Google search for '''<nowiki>[MDMA FDA "breakthrough therapy designation"]</nowiki>''' resulted in over 30,000 hits including numerous substantial articles in the Wall Street Journal, Forbes, and the FDA website itself just to name a few. I also see numerous medical publications on this matter but am unaware which of them are considered reliable sources. Obviously these studies have not yet come to conclusion but the article should reflect any substantial changes in the current state of affairs I would think. [[Special:Contributions/172.88.134.103|172.88.134.103]] ([[User talk:172.88.134.103|talk]]) 06:21, 23 April 2018 (UTC)


The best source for this claim is that there may be 5HT2A agonism, which "supposedly contributes" to "mild psychedelic hallucinations" caused by "high doses" of MDMA. That's a lot of words to say that its status as a psychedelic is pretty flimsy.
== History ==


The other sources don't support that it is one, either, just that it's commonly referred to as one. This is similar to how cocaine is called a "narcotic," a legal stipulative definition that's quite different from the scientific one.
I don't think the history segment of this article should be placed as far into the article as it is. I think it's an important enough detail to be placed as the first subtopic of the article. I am amazed as to why it is as far into the topic as it is.


I'm not arguing that MDMA isn't a psychedelic, but if these are the best sources we have I think it should be removed from the lead. [[Special:Contributions/2600:1017:B103:D814:CCC9:7381:FFDB:5A2D|2600:1017:B103:D814:CCC9:7381:FFDB:5A2D]] ([[User talk:2600:1017:B103:D814:CCC9:7381:FFDB:5A2D|talk]]) 17:51, 13 December 2023 (UTC)
23:52, 22 February 2019 (UTC)


:MDMA is not in any way, shape or form, a ''classic psychedelic'', meaning that it cannot be directly compared to [[LSD]], [[psilocybin]], or even [[mescaline]], but it ''is'' somewhat closer to mescaline than many other things that people consider to have psychedelic properties, such as [[cannabis]], [[ketamine]], [[salvia divinorum]], and even [[muscimol]]. The lead says it has "minor psychedelic properties", but that doesn't mean that it ''is'' a psychedelic. Perhaps we just need some clarification in the lead that while it has ''minor psychedelic properties'', it is not technically a psychedelic. [[User:Thoric|Thoric]] ([[User talk:Thoric|talk]]) 18:35, 13 December 2023 (UTC)
== "sold mixed with other substances" ==


== Bruxism → Chewing Gum? ==
In the first part of the page is the following sentence: "It is often sold mixed with other substances such as ephedrine, amphetamine, and methamphetamine."


Should we add that some users chew gum in order to deal with grinding teeth? Since the article is semi-protected, I wanted to check before just adding it in (especially since finding a good source for this is trickier than I though). [[User:Niplav|Niplav]] ([[User talk:Niplav|talk]]) 13:57, 7 February 2024 (UTC)
I think this used to be the case but I don't think it's generally, globally true today. The original source for this fact even states it less strongly than the article.


== The role of Danny Leclère in the production of XTC as partydrug ==
"Additionally, the illicit sale of Ecstasy makes it prone to being “cut” with other illicit and potentially toxic or deadly chemicals. Ecstasy tablets may contain other substances in addition to MDMA, such as ephedrine (a stimulant); dextromethorphan (a cough suppressant that has PCP-like effects at high doses); ketamine (an anesthetic used mostly by veterinarians that also has PCP-like effects); caffeine; cocaine; and methamphetamine."


I have a proposition to add some text regarding [[Danny Leclère]] who developed in the 1990's a formula to produce "pure XTC" as party drug and set up a worldwide illegal network to have the drugs distributed. It's because if him XTC became popular in nightlife. The formula of Leclère is still the most used in the manufacturing of (illegal) XTC. Valid/Trusted references can be found in the article about [[Danny Leclère]]. I think a short topic in the article of MDMA is advisable due to Leclère his role in production/distribution of illegal XTC. [[User:Ino mart|Ino mart]] ([[User talk:Ino mart|talk]]) 15:31, 6 March 2024 (UTC)
What's problematic here is that we don't have globally reliable data, but we could state this of course.


:is "pure XTC" MDMA? [[User:Bon courage|Bon courage]] ([[User talk:Bon courage|talk]]) 15:55, 6 March 2024 (UTC)
I'd like to restate the sentence into the following.
::According the documentary "Bad, Bad Belgium" the term "pure XTC" refers to the formula by Leclère: it is the first XTC-formula which only contains MDMA as drug. At that time, MDMA-drugs also contained other ingredients such as meta-Chlorophenylpiperazine and para-Methoxy-N-methylamphetamine.


== Section on medical use outdated, US-centric, and wrong ==
"XTC pills or MDMA crystals/powder sometimes contain other psychoactive substances. To which degree this happens and which other substances are found depends strongly on the country in which the substances are sold."


The section incorrectly reads "As of 2017, MDMA has no accepted medical indications.[where?] Before it was widely banned, it saw limited use in psychotherapy. In 2017 the United States Food and Drug Administration (FDA) approved limited research on MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD), with some preliminary evidence that MDMA may facilitate psychotherapy efficacy for PTSD.".
Sources:
https://www.ecstasydata.org/about.php
https://www.projectknow.com/discover/jagged-little-pill/


MDMA has been approved for the treatment of PTSD in Australia (https://www.tga.gov.au/news/media-releases/change-classification-psilocybin-and-mdma-enable-prescribing-authorised-psychiatrists). The accepted medical indication in this case is thus PTSD.
[[User:Niels.bom|Niels.bom]] ([[User talk:Niels.bom|talk]]) 09:46, 3 July 2019 (UTC)


Additionally, the paragraph is very US-centric, in a way that does not fit Wikipedia.
== Mydriasis listed as an adverse effect ==


Suggestion to edit the paragraph to:
I have removed this twice but some editor keeps reverting me. Every time I explained my reason for removing it, but keep getting reverted with no real justification. Unless someone can explain why [[mydriasis]] would be an '''adverse''' effect, I say it's not to be listed there. --[[User:UKER|uKER]] ([[User talk:UKER|talk]]) 12:22, 25 July 2019 (UTC)
"In 2023, MDMA was approved for the treatment of PTSD in Australia[https://www.tga.gov.au/news/media-releases/change-classification-psilocybin-and-mdma-enable-prescribing-authorised-psychiatrists]. As of June 2024, it is currently not approved for medical use in other countries." [[Special:Contributions/158.174.187.29|158.174.187.29]] ([[User talk:158.174.187.29|talk]]) 12:58, 8 June 2024 (UTC)

Latest revision as of 21:49, 8 June 2024


The BP in a medium vacuum should not be listed[edit]

The infobox currently lists the boiling point at 0.4 mmHg, which is a medium vacuum. It is not sourced, and it doesn't say whether this is the free base or what salt it is. This is nearly useless information and it isn't sourced, it should simply be removed. The melting points of the free base and any common salts, at atmospheric pressure, would be interesting data to add. Boiling point in a vacuum is silly. 209.6.225.254 (talk) 09:36, 24 November 2023 (UTC)[reply]

Is MDMA a psychedelic or not?[edit]

The best source for this claim is that there may be 5HT2A agonism, which "supposedly contributes" to "mild psychedelic hallucinations" caused by "high doses" of MDMA. That's a lot of words to say that its status as a psychedelic is pretty flimsy.

The other sources don't support that it is one, either, just that it's commonly referred to as one. This is similar to how cocaine is called a "narcotic," a legal stipulative definition that's quite different from the scientific one.

I'm not arguing that MDMA isn't a psychedelic, but if these are the best sources we have I think it should be removed from the lead. 2600:1017:B103:D814:CCC9:7381:FFDB:5A2D (talk) 17:51, 13 December 2023 (UTC)[reply]

MDMA is not in any way, shape or form, a classic psychedelic, meaning that it cannot be directly compared to LSD, psilocybin, or even mescaline, but it is somewhat closer to mescaline than many other things that people consider to have psychedelic properties, such as cannabis, ketamine, salvia divinorum, and even muscimol. The lead says it has "minor psychedelic properties", but that doesn't mean that it is a psychedelic. Perhaps we just need some clarification in the lead that while it has minor psychedelic properties, it is not technically a psychedelic. Thoric (talk) 18:35, 13 December 2023 (UTC)[reply]

Bruxism → Chewing Gum?[edit]

Should we add that some users chew gum in order to deal with grinding teeth? Since the article is semi-protected, I wanted to check before just adding it in (especially since finding a good source for this is trickier than I though). Niplav (talk) 13:57, 7 February 2024 (UTC)[reply]

The role of Danny Leclère in the production of XTC as partydrug[edit]

I have a proposition to add some text regarding Danny Leclère who developed in the 1990's a formula to produce "pure XTC" as party drug and set up a worldwide illegal network to have the drugs distributed. It's because if him XTC became popular in nightlife. The formula of Leclère is still the most used in the manufacturing of (illegal) XTC. Valid/Trusted references can be found in the article about Danny Leclère. I think a short topic in the article of MDMA is advisable due to Leclère his role in production/distribution of illegal XTC. Ino mart (talk) 15:31, 6 March 2024 (UTC)[reply]

is "pure XTC" MDMA? Bon courage (talk) 15:55, 6 March 2024 (UTC)[reply]
According the documentary "Bad, Bad Belgium" the term "pure XTC" refers to the formula by Leclère: it is the first XTC-formula which only contains MDMA as drug. At that time, MDMA-drugs also contained other ingredients such as meta-Chlorophenylpiperazine and para-Methoxy-N-methylamphetamine.

Section on medical use outdated, US-centric, and wrong[edit]

The section incorrectly reads "As of 2017, MDMA has no accepted medical indications.[where?] Before it was widely banned, it saw limited use in psychotherapy. In 2017 the United States Food and Drug Administration (FDA) approved limited research on MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD), with some preliminary evidence that MDMA may facilitate psychotherapy efficacy for PTSD.".

MDMA has been approved for the treatment of PTSD in Australia (https://www.tga.gov.au/news/media-releases/change-classification-psilocybin-and-mdma-enable-prescribing-authorised-psychiatrists). The accepted medical indication in this case is thus PTSD.

Additionally, the paragraph is very US-centric, in a way that does not fit Wikipedia.

Suggestion to edit the paragraph to: "In 2023, MDMA was approved for the treatment of PTSD in Australia[1]. As of June 2024, it is currently not approved for medical use in other countries." 158.174.187.29 (talk) 12:58, 8 June 2024 (UTC)[reply]

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