Cannabis Ruderalis

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== Names for different combinations of MDMA + other drugs ==

In the article, the combination of MDMA with LSD, psilocybin mushrooms or ketamine are all given the name "candy-flip". However, from experience on forums and such I have gathered that MDMA + LSD = Candy Flip, MDMA + psilocybin = Hippy Flip and MDMA + ketamine = Kitty Flip. Unfortunately I do not have concrete sources, since this is something I have encountered so often that listing all instances would be impossible, however the main forum I have encountered these names at is Reddit.com

== Name ==
The phrase "commonly known as ecstasy (E) or molly" is misleading, given the reported increasing adulteration of illegally marketed drugs termed "ecstasy", which are likely to be "enhanced" with ketamine, caffeine, BZP, and other narcotics and stimulants.

I suggest a cautionary description would be better, i.e. "3,4-Methyl​enedioxy​methamphetamine (MDMA),[note 1] is a psychoactive drug primarily used for recreational purposes.[13] Drugs distributed as "ecstasy (E) or molly" are normally purported to contain MDMA, but are often adulterated by ketamine, caffeine, BZP, and other narcotics and stimulants." <!-- Template:Unsigned --><span class="autosigned" style="font-size:85%;">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Carusus|Carusus]] ([[User talk:Carusus#top|talk]] • [[Special:Contributions/Carusus|contribs]]) 14:31, 10 February 2021 (UTC)</span> <!--Autosigned by SineBot-->

== Evidence for PTSD efficacy ==

{{edit semi-protected|answered=yes}}
The research section currently states:

''MDMA has been claimed to be useful in treating post-traumatic stress disorder, but such claims are not backed by good evidence.[181]''

Source 181 actually states:

''It has been suggested that MDMA, for example, possesses characteristics that make it uniquely useful for the treatment of PTSD [122]; the same has been argued for ibogaine in the treatment of SUD [42]. The high heterogeneity of the articles included in this review do not provide sufficient evidence to establish these relations''


== Edit request 19 July 2023 ==
This is not the same thing. The study does not claim that the evidence of usefulness is limited, but that the evidence for ''unique'' usefulness is limited.


"Endogenous" is used in the introduction. It's neither linked nor defined. It's a $5 word. A $0.50 word would be better. Failing that, it would be helpful if it were a link to something - Wiktionary or an appropriate Wikipedia page. Thanks! [[Special:Contributions/108.64.118.44|108.64.118.44]] ([[User talk:108.64.118.44|talk]]) 00:48, 20 July 2023 (UTC)
Moreover, a [https://pubmed.ncbi.nlm.nih.gov/32931403/ newer review] that is more specific to the topic and includes more trials states the following:
:{{done}} --[[User:WikiLinuz|<span style="font-family:Optima;color:#292928;">'''Wiki'''<span style="color:red;">'''''Linuz'''''</span></span>]] {[[User_talk:WikiLinuz|<span style="font-family:Optima;">talk</span>]]} 01:11, 20 July 2023 (UTC)


== The BP in a medium vacuum should not be listed ==
''The evidence for MDMA in combination with psychotherapy as a PTSD treatment was ranked "moderate"''


The infobox currently lists the boiling point at 0.4 mmHg, which is a medium vacuum. It is not sourced, and it doesn't say whether this is the free base or what salt it is. This is nearly useless information and it isn't sourced, it should simply be removed. The melting points of the free base and any common salts, at atmospheric pressure, would be interesting data to add. Boiling point in a vacuum is silly. [[Special:Contributions/209.6.225.254|209.6.225.254]] ([[User talk:209.6.225.254|talk]]) 09:36, 24 November 2023 (UTC)
I propose that the last sentence in the research section states:


== Is MDMA a psychedelic or not? ==
''MDMA in combination with psychotherapy has been studied as a treatment for PTSD, and four clinical trials provide moderate evidence in support of this''


The best source for this claim is that there may be 5HT2A agonism, which "supposedly contributes" to "mild psychedelic hallucinations" caused by "high doses" of MDMA. That's a lot of words to say that its status as a psychedelic is pretty flimsy.
[[User:Juniusbrutus|Juniusbrutus]] ([[User talk:Juniusbrutus|talk]]) 04:10, 21 February 2021 (UTC)
:[[File:Yes check.svg|20px|link=|alt=]] '''Done'''<!-- Template:ESp --> the newer review should also be cited, right? You didn't make that clear in your request, but if you think it should be cited in the article, feel free to re-open. [[User:Elliot321|Elliot321]] ([[User_talk:Elliot321|talk]] &#124; [[Special:Contributions/Elliot321|contribs]]) 17:08, 21 February 2021 (UTC)


The other sources don't support that it is one, either, just that it's commonly referred to as one. This is similar to how cocaine is called a "narcotic," a legal stipulative definition that's quite different from the scientific one.
== Semi-protected edit request on 22 February 2021 ==


I'm not arguing that MDMA isn't a psychedelic, but if these are the best sources we have I think it should be removed from the lead. [[Special:Contributions/2600:1017:B103:D814:CCC9:7381:FFDB:5A2D|2600:1017:B103:D814:CCC9:7381:FFDB:5A2D]] ([[User talk:2600:1017:B103:D814:CCC9:7381:FFDB:5A2D|talk]]) 17:51, 13 December 2023 (UTC)
{{edit semi-protected|MDMA|answered=yes}}
It is misrepresentative to state only that MDMA is primarily used for recreational purposes in the introductory sentence. Please change "primarily used for recreational purposes" to "primarily used for recreational and therapeutic purposes". It is also worth changing the end of the introduction: "MDMA is illegal in most countries and, as of 2018, has no approved medical uses." Afterwards, please add, "However, in 2017 the FDA granted breakthrough therapy designation for its use with psychotherapy for PTSD." [[Special:Contributions/209.6.143.81|209.6.143.81]] ([[User talk:209.6.143.81|talk]]) 21:23, 22 February 2021 (UTC)
: {{not done}}. Please provide a [[WP:RS|reliable source]] showing that MDMA is ''actually used'' for therapeutic uses. Just a designation does not count. [[User:Ganbaruby|<span style="color:#960596">◢</span> <b><i style="background-color:#F7E3F7; color:#960596"> Ganbaruby! </i></b>]] <small>([[User talk:Ganbaruby|Say hi!]])</small> 08:17, 23 February 2021 (UTC)


:MDMA is not in any way, shape or form, a ''classic psychedelic'', meaning that it cannot be directly compared to [[LSD]], [[psilocybin]], or even [[mescaline]], but it ''is'' somewhat closer to mescaline than many other things that people consider to have psychedelic properties, such as [[cannabis]], [[ketamine]], [[salvia divinorum]], and even [[muscimol]]. The lead says it has "minor psychedelic properties", but that doesn't mean that it ''is'' a psychedelic. Perhaps we just need some clarification in the lead that while it has ''minor psychedelic properties'', it is not technically a psychedelic. [[User:Thoric|Thoric]] ([[User talk:Thoric|talk]]) 18:35, 13 December 2023 (UTC)
== Semi-protected edit request on 25 February 2021 ==


== Bruxism → Chewing Gum? ==
{{edit semi-protected|MDMA|answered=yes}}
MDMA was not first synthesized by Merck, it was first synthesized by Alexander “Sasha” Shulgin. [[Special:Contributions/75.142.234.192|75.142.234.192]] ([[User talk:75.142.234.192|talk]]) 06:25, 25 February 2021 (UTC)
:[[File:Red information icon with gradient background.svg|20px|link=|alt=]] '''Not done:''' please provide [[Wikipedia:Reliable sources|reliable sources]] that support the change you want to be made.<!-- Template:ESp --> [[User:Robertsky|– robertsky]] ([[User talk:Robertsky|talk]]) 08:58, 25 February 2021 (UTC)


Should we add that some users chew gum in order to deal with grinding teeth? Since the article is semi-protected, I wanted to check before just adding it in (especially since finding a good source for this is trickier than I though). [[User:Niplav|Niplav]] ([[User talk:Niplav|talk]]) 13:57, 7 February 2024 (UTC)
== Semi-protected edit request on 30 June 2021 ==


== The role of Danny Leclère in the production of XTC as partydrug ==
{{edit semi-protected|MDMA|answered=no}}
In the last sentence of the summary, change "In the US the Food And Drug Association is currently evaluating the drug for clinical use.[23]" to "In the US the Food and Drug Administration is currently evaluating the drug for clinical use.[23]"


I have a proposition to add some text regarding [[Danny Leclère]] who developed in the 1990's a formula to produce "pure XTC" as party drug and set up a worldwide illegal network to have the drugs distributed. It's because if him XTC became popular in nightlife. The formula of Leclère is still the most used in the manufacturing of (illegal) XTC. Valid/Trusted references can be found in the article about [[Danny Leclère]]. I think a short topic in the article of MDMA is advisable due to Leclère his role in production/distribution of illegal XTC. [[User:Ino mart|Ino mart]] ([[User talk:Ino mart|talk]]) 15:31, 6 March 2024 (UTC)
For clarity, "Food And Drug Association" should be "Food and Drug Administration"


Verified through cited article <ref>https://www.nytimes.com/2021/05/03/health/mdma-approval.html</ref> [[User:IsbenTakesTea|IsbenTakesTea]] ([[User talk:IsbenTakesTea|talk]]) 16:53, 30 June 2021 (UTC)
:is "pure XTC" MDMA? [[User:Bon courage|Bon courage]] ([[User talk:Bon courage|talk]]) 15:55, 6 March 2024 (UTC)
::According the documentary "Bad, Bad Belgium" the term "pure XTC" refers to the formula by Leclère: it is the first XTC-formula which only contains MDMA as drug. At that time, MDMA-drugs also contained other ingredients such as meta-Chlorophenylpiperazine and para-Methoxy-N-methylamphetamine.
:That whole sentence could do with a rewrite. It makes it sound like the FDA is driving the change when it's actually in clinical trial for therapeutic use. That source should instead be used to provide additional information in the [[MDMA#Research|Research]] and [[MDMA#Medical|Medical]] sections. I plan on taking a closer look at this later, but if someone else patrolling edit requests wants to take a stab at it, go for it. [[User:Living Concrete|Living Concrete]] ([[User talk:Living Concrete|talk]]) 17:22, 30 June 2021 (UTC)

Revision as of 23:15, 19 March 2024


Edit request 19 July 2023

"Endogenous" is used in the introduction. It's neither linked nor defined. It's a $5 word. A $0.50 word would be better. Failing that, it would be helpful if it were a link to something - Wiktionary or an appropriate Wikipedia page. Thanks! 108.64.118.44 (talk) 00:48, 20 July 2023 (UTC)[reply]

 Done --WikiLinuz {talk} 01:11, 20 July 2023 (UTC)[reply]

The BP in a medium vacuum should not be listed

The infobox currently lists the boiling point at 0.4 mmHg, which is a medium vacuum. It is not sourced, and it doesn't say whether this is the free base or what salt it is. This is nearly useless information and it isn't sourced, it should simply be removed. The melting points of the free base and any common salts, at atmospheric pressure, would be interesting data to add. Boiling point in a vacuum is silly. 209.6.225.254 (talk) 09:36, 24 November 2023 (UTC)[reply]

Is MDMA a psychedelic or not?

The best source for this claim is that there may be 5HT2A agonism, which "supposedly contributes" to "mild psychedelic hallucinations" caused by "high doses" of MDMA. That's a lot of words to say that its status as a psychedelic is pretty flimsy.

The other sources don't support that it is one, either, just that it's commonly referred to as one. This is similar to how cocaine is called a "narcotic," a legal stipulative definition that's quite different from the scientific one.

I'm not arguing that MDMA isn't a psychedelic, but if these are the best sources we have I think it should be removed from the lead. 2600:1017:B103:D814:CCC9:7381:FFDB:5A2D (talk) 17:51, 13 December 2023 (UTC)[reply]

MDMA is not in any way, shape or form, a classic psychedelic, meaning that it cannot be directly compared to LSD, psilocybin, or even mescaline, but it is somewhat closer to mescaline than many other things that people consider to have psychedelic properties, such as cannabis, ketamine, salvia divinorum, and even muscimol. The lead says it has "minor psychedelic properties", but that doesn't mean that it is a psychedelic. Perhaps we just need some clarification in the lead that while it has minor psychedelic properties, it is not technically a psychedelic. Thoric (talk) 18:35, 13 December 2023 (UTC)[reply]

Bruxism → Chewing Gum?

Should we add that some users chew gum in order to deal with grinding teeth? Since the article is semi-protected, I wanted to check before just adding it in (especially since finding a good source for this is trickier than I though). Niplav (talk) 13:57, 7 February 2024 (UTC)[reply]

The role of Danny Leclère in the production of XTC as partydrug

I have a proposition to add some text regarding Danny Leclère who developed in the 1990's a formula to produce "pure XTC" as party drug and set up a worldwide illegal network to have the drugs distributed. It's because if him XTC became popular in nightlife. The formula of Leclère is still the most used in the manufacturing of (illegal) XTC. Valid/Trusted references can be found in the article about Danny Leclère. I think a short topic in the article of MDMA is advisable due to Leclère his role in production/distribution of illegal XTC. Ino mart (talk) 15:31, 6 March 2024 (UTC)[reply]

is "pure XTC" MDMA? Bon courage (talk) 15:55, 6 March 2024 (UTC)[reply]
According the documentary "Bad, Bad Belgium" the term "pure XTC" refers to the formula by Leclère: it is the first XTC-formula which only contains MDMA as drug. At that time, MDMA-drugs also contained other ingredients such as meta-Chlorophenylpiperazine and para-Methoxy-N-methylamphetamine.

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