Salpingectomy refers to the surgical removal of a Fallopian tube. The procedure was first performed by Lawson Tait in patients with a bleeding tubal pregnancy; this procedure has since saved the lives of countless women. Other indications for a salpingectomy include infected tubes, (as in a hydrosalpinx) or as part of the surgical procedure for tubal cancer. Salpingectomy is different than a salpingostomy, a procedure where an opening is made into the tube to remove an ectopic pregnancy, but the tube itself is not removed.

Salpingectomy has been traditionally done via a laparotomy, more recently however, laparoscopic salpingectomies have become more common as part of minimally invasive surgery.

Salpingectomy is commonly done in conjunction as part of a "complete" hysterectomy - a procedure called a salpingo-oophorectomy where the uterus and both ovaries and Fallopian tubes are removed in one operation.