Régine Chassagne is a Canadian musician and singer. Her family is originally from Haiti, but she grew up in Montreal. She is a member of the indie rock band The Arcade Fire. She plays many instruments on stage, including the accordion, drums, the xylophone and keyboards. She is married to the Arcade Fire's lead singer Win Butler.

She has also been involved with a medieval band called Les Jongleurs de la Mandragore, and a jazz band, Azúcar.

As well, Regine wrote the music for the two-minute David Uloth sketch:"The Shine" [1]

Trivia

• Contributed to the UNICEF benefit project as part the North American Hallowe'en Prevention Intiative, performing the song "Do They Know It's Hallowe'en?" along with Win Butler.