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Revision as of 17:18, 28 February 2019
Introduction
Cannabis (/ˈkænəbɪs/) is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: Cannabis sativa, C. indica, and C. ruderalis. Alternatively, C. ruderalis may be included within C. sativa, all three may be treated as subspecies of C. sativa, or C. sativa may be accepted as a single undivided species. The genus is widely accepted as being indigenous to and originating from Asia.
The plant is also known as hemp, although this term is often used to refer only to varieties of Cannabis cultivated for non-drug use. Cannabis has long been used for hemp fibre, hemp seeds and their oils, hemp leaves for use as vegetables and as juice, medicinal purposes, and as a recreational drug. Industrial hemp products are made from cannabis plants selected to produce an abundance of fibre. Various cannabis strains have been bred, often selectively to produce high or low levels of tetrahydrocannabinol (THC), a cannabinoid and the plant's principal psychoactive constituent. Compounds such as hashish and hash oil are extracted from the plant. (Full article...)
Selected general articles
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Hemp, or industrial hemp, is a plant in the botanical class of Cannabis sativa cultivars grown specifically for industrial and consumable use. It can be used to make a wide range of products. Along with bamboo, hemp is among the fastest growing plants on Earth. It was also one of the first plants to be spun into usable fiber 50,000 years ago. It can be refined into a variety of commercial items, including paper, rope, textiles, clothing, biodegradable plastics, paint, insulation, biofuel, food, and animal feed.
Although chemotype I cannabis and hemp (types II, III, IV, V) are both Cannabis sativa and contain the psychoactive component tetrahydrocannabinol (THC), they represent distinct cultivar groups, typically with unique phytochemical compositions and uses. Hemp typically has lower concentrations of total THC and may have higher concentrations of cannabidiol (CBD), which potentially mitigates the psychoactive effects of THC. The legality of hemp varies widely among countries. Some governments regulate the concentration of THC and permit only hemp that is bred with an especially low THC content into commercial production. (Full article...) -
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Cannabis, also known as marijuana or weed among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by smoking, vaporizing, within food, or as an extract.
Cannabis has various mental and physical effects, which include euphoria, altered states of mind and sense of time, difficulty concentrating, impaired short-term memory, impaired body movement (balance and fine psychomotor control), relaxation, and an increase in appetite. Onset of effects is felt within minutes when smoked, but may take up to 90 minutes when eaten (as orally consumed drugs must be digested and absorbed). The effects last for two to six hours, depending on the amount used. At high doses, mental effects can include anxiety, delusions (including ideas of reference), hallucinations, panic, paranoia, and psychosis. There is a strong relation between cannabis use and the risk of psychosis, though the direction of causality is debated. Physical effects include increased heart rate, difficulty breathing, nausea, and behavioral problems in children whose mothers used cannabis during pregnancy; short-term side effects may also include dry mouth and red eyes. Long-term adverse effects may include addiction, decreased mental ability in those who started regular use as adolescents, chronic coughing, susceptibility to respiratory infections, and cannabinoid hyperemesis syndrome.
Cannabis is mostly used recreationally or as a medicinal drug, although it may also be used for spiritual purposes. In 2013, between 128 and 232 million people used cannabis (2.7% to 4.9% of the global population between the ages of 15 and 65). It is the most commonly used largely-illegal drug in the world, with the highest use among adults in Zambia, the United States, Canada, and Nigeria. Since the 1970s, the potency of illicit cannabis has increased, with THC levels rising and CBD levels dropping. (Full article...) -
Image 3The effect of cannabis on time perception has been studied with inconclusive results. Studies show consistently throughout the literature that most cannabis users self-report the experience of a slowed perception of time. In the laboratory, researchers have confirmed the effect of cannabis on the perception of time in both humans and animals. Studies have sought to explain how cannabis changes the internal clock. Matthew et al. (1998) looked at the cerebellum, positing a relationship between cerebellar blood flow and the distortion of time perception. (Full article...)
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Cannabis concentrate, also called marijuana concentrate, marijuana extract, or cannabis extract, is a tetrahydrocannabinol (THC) and/or cannabidiol (CBD) concentrated mass. Cannabis concentrates contain high THC levels that range from 40% to over 90%, stronger in THC content than high-grade marijuana, which normally measures around 20% THC levels.
Volatile solvents, such as ethanol, butane, propane or hexane, may be used to prepare extracts, but can and will possibly lead to fire and explosion hazards in uncontrolled environments. Supercritical carbon dioxide (CO2) extraction alleviates concerns of fire and explosion and results in a high-quality product.
Legally produced concentrates for retail sale in legalized U.S. states are often packaged in small lip balm-sized containers. (Full article...) -
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The Single Convention on Narcotic Drugs, 1961 (Single Convention, 1961 Convention, or C61) is an international treaty that controls activities (cultivation, production, supply, trade, transport) of specific narcotic drugs and lays down a system of regulations (licenses, measures for treatment, research, etc.) for their medical and scientific uses; it also establishes the International Narcotics Control Board.
The Single Convention was adopted in 1961 and amended in 1972. As of 2022, the Single Convention as amended has been ratified by 186 countries. The convention has since been supplemented by the 1971 Convention on Psychotropic Substances, which controls LSD, MDMA, and other psychoactive pharmaceuticals, and the 1988 United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. (Full article...) -
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Different religions have varying stances on the use of cannabis, historically and presently. In ancient history some religions used cannabis as an entheogen, particularly in the Indian subcontinent where the tradition continues on a more limited basis.
In the modern era Rastafari use cannabis as a sacred herb. Meanwhile, religions with prohibitions against intoxicants, including Buddhism, Baháʼí, and Latter-day Saints (Mormons) forbid usage except with a prescription from a doctor; others have opposed the use of cannabis by members, or in some cases opposed the liberalization of cannabis laws. Other groups, such as some Protestant and Jewish factions, and certain Islamic schools (madhhab) have supported the use of medicinal cannabis. (Full article...) -
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The Global Marijuana March (GMM), also referred to as the Million Marijuana March (MMM), is an annual rally held at different locations around the world on the first Saturday in May. A notable event in cannabis culture, it is associated with cannabis-themed events, which may include marches, meetings, rallies, raves, concerts, festivals, and attempts at educational outreach.
The first Global Marijuana March was held in 1999. Since then, hundreds of thousands of people have participated in over 1034 different cities in 85 nations and subnational areas. Locally, the Global Marijuana March is associated with names including Global Cannabis March, World Cannabis Day, Cannabis Liberation Day, Global Space Odyssey, Ganja Day, J Day, and Million Blunts March. (Full article...) -
Image 9Aotearoa Legalise Cannabis Party (ALCP), also known as the Cannabis Party, is a political party in New Zealand. It is dedicated to the legalisation of cannabis for medical, recreational and industrial use. It was founded in 1996 and has stood in every general election since, but has never won representation in Parliament. Several of its members have gone on to political success after leaving the party. (Full article...)
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A budtender is a title of a staff member who works within a dispensary or store where medical or recreational cannabis is sold. Their job is to offer suggestions to customers, answer questions, handle products and showcase products being sold. (Full article...) -
Image 11Cannabis Law Reform (CLEAR), formerly the Legalise Cannabis Alliance, is a United Kingdom lobby group which campaigns to end the prohibition of cannabis. The group was founded in 1997 and reformed as CLEAR in 2011. It campaigned in a number of elections until it was statutorily de-registered by the Electoral Commission in November 2013. (Full article...)
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Cannabis indica is an annual plant species in the family Cannabaceae indigenous to the Hindu Kush mountains of Southern Asia. The plant produces large amounts of tetrahydrocannabinol (THC)[better source needed] and tetrahydrocannabivarin (THCV), with total cannabinoid levels being as high as 53.7%[scientific citation needed]. It is now widely grown in China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa, and is cultivated for purposes including hashish in India. The high concentrations of THC or THCV provide euphoric effects making it popular for use both as a recreational drug, alternative medicine, and a clinical research drug. (Full article...) -
Image 13A cannabis cookbook is a cookbook for preparing cannabis edibles, often in the form of a baking guide. According to The New York Times, baking recipes are popular because "[THC] dosing is easier to control in batter-based dishes or chocolate". Such cookbooks existed prior to United States legalization; The Alice B. Toklas Cook Book published in 1954, for instance, or The Marijuana Chef Cookbook published in 2001 under the pseudonym S.T. Oner, but became more commonplace after California and other states legalized in the 2010s. Notable chefs like Laurie Wolf and Jasmine Shimoda have created or contributed to cannabis cookbooks. (Full article...)
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Image 14In the United States, the removal of cannabis from Schedule I of the Controlled Substances Act, the category reserved for drugs that have "no currently accepted medical use", is a proposed legal and administrative change in cannabis-related law at the federal level. After being proposed repeatedly since 1972, in 2024, the US Department of Justice announced it was initiating rulemaking to reschedule cannabis to Schedule III of the Controlled Substances Act. (Full article...)
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NORML New Zealand is a cannabis law reform organisation in New Zealand. It is a National Chapter of the National Organization for the Reform of Marijuana Laws (NORML). (Full article...) -
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The legality of cannabis for medical and recreational use varies by country, in terms of its possession, distribution, and cultivation, and (in regards to medical) how it can be consumed and what medical conditions it can be used for. These policies in most countries are regulated by three United Nations treaties: the 1961 Single Convention on Narcotic Drugs, the 1971 Convention on Psychotropic Substances, and the 1988 Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. Cannabis was reclassified in 2020 to a Schedule I-only drug under the Single Convention treaty (from being a Schedule I and IV drug previously), with the schedules from strictest to least being IV, I, II, and III. As a Schedule I drug under the treaty, countries can allow the medical use of cannabis but it is considered to be an addictive drug with a serious risk of abuse.
The use of cannabis for recreational purposes is prohibited in most countries; however, many have adopted a policy of decriminalization to make simple possession a non-criminal offense (often similar to a minor traffic violation). Others have much more severe penalties such as some Middle Eastern and Far Eastern countries where possession of even small amounts is punished by imprisonment for several years. Countries that have legalized recreational use of cannabis are Canada, Georgia, Germany, Luxembourg, Malta, Mexico, South Africa, Thailand, and Uruguay, plus 24 states, 3 territories, and the District of Columbia in the United States and the Australian Capital Territory in Australia. Commercial sale of recreational cannabis is legalized nationwide in three countries (Canada, Thailand, and Uruguay) and in all subnational U.S. jurisdictions that have legalized possession except Virginia and Washington, D.C. A policy of limited enforcement has also been adopted in many countries, in particular the Netherlands where the sale of cannabis is tolerated at licensed coffeeshops.
Countries that have legalized medical use of cannabis include Albania, Argentina, Australia, Barbados, Brazil, Canada, Chile, Colombia, Costa Rica, Croatia, Cyprus, Czech Republic, Denmark, Ecuador, Finland, Georgia, Germany, Greece, Ireland, Israel, Italy, Jamaica, Lebanon, Luxembourg, Malawi, Malta, Mexico, the Netherlands, New Zealand, North Macedonia, Norway, Panama, Peru, Poland, Portugal, Rwanda, Saint Vincent and the Grenadines, San Marino, South Africa, Spain, Sri Lanka, Switzerland, Thailand, Ukraine, the United Kingdom, Uruguay, Vanuatu, Zambia, and Zimbabwe. Others have more restrictive laws that allow only the use of certain cannabis-derived pharmaceuticals, such as Sativex, Marinol, or Epidiolex. In the United States, 38 states, 4 territories, and the District of Columbia have legalized the medical use of cannabis, but at the federal level its use remains prohibited. (Full article...) -
Image 18Adult lifetime cannabis use by country is the lifetime prevalence of cannabis use among all adults in surveys among the general population. Lifetime prevalence means any use of cannabis during a person's life. (Full article...)
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The Multidisciplinary Association for Psychedelic Studies (MAPS) is an American nonprofit organization working to raise awareness and understanding of psychedelic substances. MAPS was founded in 1986 by Rick Doblin and is now based in San Jose, California.
MAPS helps scientists design, fund, and obtain regulatory approval for studies of the safety and effectiveness of a number of controlled substances. MAPS works closely with government regulatory authorities worldwide such as the United States Food and Drug Administration (FDA) and the European Medicines Agency (EMA) to ensure that all of its sponsored research protocols conform to ethical and procedural guidelines for clinical drug research. Included in MAPS' research efforts are MDMA (methylenedioxymethamphetamine) for the treatment of posttraumatic stress disorder (PTSD); LSD and psilocybin for the treatment of anxiety, cluster headaches, and depression associated with end-of-life issues; ibogaine for the treatment of opiate addiction, ayahuasca for the treatment of drug addiction and PTSD; medical cannabis for PTSD; and alternative delivery systems for medical cannabis such as vaporizers and water pipes. MAPS officials say the organization's ultimate goal is to establish a network of clinics where these and other treatments can be provided together with other therapies under the guidance of trained, licensed physicians and therapists. In December 2023, MAPS submitted a New Drug Application (NDA) to the FDA for MDMA-assisted psychotherapy.
In addition to sponsoring scientific research, MAPS organizes continuing medical education (CME) conferences, sponsors and presents lectures and seminars on the state of psychedelic and medical marijuana research, provides psychedelic harm reduction services through the Zendo Project at events such as music festivals and Burning Man, and publishes a triannual magazine-style publication, the MAPS Bulletin, with updates about its ongoing research efforts, legal struggles, and educational initiatives. MAPS also publishes books dealing with the science, history, and culture of psychedelic research and psychedelic therapy. (Full article...) -
Image 21An endocannabinoid enhancer (eCBE) is a type of cannabinoidergic drug that enhances the activity of the endocannabinoid system by increasing extracellular concentrations of endocannabinoids. Examples of different types of eCBEs include fatty acid amide hydrolase (FAAH) inhibitors, monoacylglycerol lipase (MAGL) inhibitors, and endocannabinoid transporter (eCBT) inhibitors (or "endocannabinoid reuptake inhibitors" ("eCBRIs")). An example of an actual eCBE is AM404, the active metabolite of the analgesic paracetamol (acetaminophen; Tylenol) and a dual FAAH inhibitor and eCBRI. (Full article...)
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A chalice, also known as a wisdom chalice or chillum chalice, is a type of cannabis smoking pipe used most often by members of the Jamaican Rastafari movement. It is a type of water pipe used for smoking. (Full article...) -
Image 23Cannabis product testing is a form of product testing analyzes the quality of cannabis extracts, edibles, and THC and CBD levels in an emergent consumer market eager to sell adult use products. Analytical chemistry and microbiology laboratories are important entities in consumer protection. These labs not only determine the condition and viability of cannabinoids, water content, heavy metals, pesticides, terpenes, yeast, but also the presence of mold, mycotoxins, and solvents. These laboratories emerged when advocates of cannabis testing raised concerns about potential contaminants.
The popularity of cannabis and cannabinoid products continues to escalate following the legalization of cannabinoid products in the United States since 2012.
By 2020, the majority of the U.S. population can purchase cannabis and cannabinoid products as easily as alcohol. But exposure to contaminants is often overlooked. Limited regulation threatens product safety in the "gold rush" era of a fast-growing cannabis industry. Analytical chemistry and microbiology testing that protects consumer safety and prevents unfair practices becomes an added cost that most startups avoid due to the lack of oversight of recreational and medicinal cannabis in the United States. Advanced analytical testing is critical given trade-offs between safety and quality in cannabinoid therapeutics and nutraceuticals. Product or compliance testing determines the chemical makeup and overall quality of the formulation before the sale of products. (Full article...)Since 2012, ten states (Colorado, Oregon, Washington, Alaska, California, Nevada, Maine, Massachusetts, Vermont, and, in November 2018, by popular referendum, Michigan) and the District of Columbia have legalized recreational cannabis consumption and, except for the District of Columbia and Vermont, acted to implement legislation that also legalizes commercial production. By 2016, 23 states had legalized medical cannabis. Additionally, a number of states, as far back as the 1960s, have decriminalized the possession of small quantities of cannabis for personal use.
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Image 24Two main questions arise in the law surrounding driving after having ingested cannabis: (1) whether cannabis actually impairs driving ability, and (2) whether the common practice of testing for THC (the main psychoactive substance in cannabis) is a reliable means to measure impairment. On the first question, studies are mixed. Several recent, extensive studies–including one conducted by the National Highway Traffic Safety Administration and one conducted by the American Automobile Association (AAA)–show that drivers with detectable THC in their blood are no more likely to cause car crashes than drivers with no amount of THC in their blood. Others show that cannabis can impair certain abilities important to safe driving (such as reaction time, divided attention, and cognitive functions)–but no studies have been able to show that this increases the actual risk of crashing, or that drivers with THC in their blood cause a disproportionate number of crashes. On the second question, the studies that have been conducted so far have consistently found that THC blood levels and degree of impairment are not closely related. No known relationship between blood levels of THC (the main psychoactive substance in cannabis) and increased relative crash risk, or THC blood levels and level of driving impairment, has been shown by single-crash or classic-control studies. Thus, even though it is possible that cannabis impairs driving ability to some extent, there are currently no reliable means to test or measure whether a driver was actually impaired.
Nonetheless, policymakers in the United States have generally dealt with cannabis-and-driving criminalization by importing the alcohol DUI regime into the cannabis context. This has led to complications down the road when cannabis-driving cases land in criminal court because cannabis detection science differs vastly from alcohol detection science. For example, blood alcohol content (BAC) has similar rates of absorption, distribution, and elimination across all humans, and there is also a fairly good correlation between BAC and level of impairment (in other words, impairment increases when BAC increases, and impairment decreases when BAC decreases). This has allowed law enforcement to use tools like breathalyzers and blood tests in criminal court because alcohol concentration is a relatively reliable indicator of how recently and how much alcohol was consumed. In contrast, THC levels can vary widely depending on the means of ingestion, THC is metabolized at an exponentially declining rate (as opposed to the steady metabolization rate for alcohol), and there is very poor correlation of THC blood levels with impairment. As stated in a report to Congress produced by the U.S. Department of Transportation's National Highway Traffic Safety Administration, "[I]n contrast to the situation with alcohol, someone can show little or no impairment at a THC level at which someone else may show a greater degree of impairment." The report also noted that, in some studies, THC was detectable as late as 30 days after ingestion–even though the acute psychoactive effects of cannabis last only for a few hours. (Full article...) -
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ADPF 187 (June 15, 2011), is a landmark Brazil Supreme Court case. The rapporteur Celso de Mello voted in favor of protests of decriminalization of drugs. (Full article...)
Did you know...
- ... that the 47 in the marijuana strain AK-47 may refer to the number of days between its planting and harvest?
- ... that American teacher Marc Fogel was sentenced to 14 years in Russian prison for possessing a small amount of marijuana, but has gotten little public attention compared to Brittney Griner?
- ... that when asked about the secret to her longevity, 91-year-old Shatzi Weisberger said she smokes marijuana every night?
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Selected images
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Image 3Male Cannabis flower buds (from Cannabis)
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Image 6A male hemp plant (from Cannabis)
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Image 7Relative size of varieties of Cannabis (from Cannabis)
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Image 8Top of Cannabis plant in vegetative growth stage (from Cannabis)
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Image 9Comparison of physical harm and dependence regarding various drugs (from Cannabis)
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Image 10A dried bud, typical of what is sold for recreational use
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Image 11Dense raceme of female flowers typical of drug-type varieties of Cannabis (from Cannabis)
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Image 15Cannabis sativa stem longitudinal section (from Cannabis)
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