Cannabis Ruderalis

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| CAS_number =
| CAS_number =
| PubChem = 11714280
| PubChem = 11714280
| ChemSpiderID = 9889001


<!--Chemical data-->
<!--Chemical data-->
| C=38 | H=60 | N=2 | O=5
| C=38 | H=60 | N=2 | O=5
| molecular_weight = 624.891 g/mol
| molecular_weight = 624.891 g/mol
| smiles = CC(C)N(C(C)C)CCCC(=O)Oc(c1C2CC=3C)cc(C(C)(C)CCCCC(=O)N4CCOCC4)cc1OC(C)(C)C2CC=3
| smiles = O=C(N1CCOCC1)CCCCC(c3cc2OC([C@@H]4C/C=C(\C[C@H]4c2c(OC(=O)CCCN(C(C)C)C(C)C)c3)C)(C)C)(C)C
| InChI = 1/C38H60N2O5/c1-26(2)40(27(3)4)18-12-14-35(42)44-32-24-29(37(6,7)17-11-10-13-34(41)39-19-21-43-22-20-39)25-33-36(32)30-23-28(5)15-16-31(30)38(8,9)45-33/h15,24-27,30-31H,10-14,16-23H2,1-9H3/t30-,31-/m1/s1
| InChIKey = OAFUHIZKKMQSAB-FIRIVFDPBS
| StdInChI = 1S/C38H60N2O5/c1-26(2)40(27(3)4)18-12-14-35(42)44-32-24-29(37(6,7)17-11-10-13-34(41)39-19-21-43-22-20-39)25-33-36(32)30-23-28(5)15-16-31(30)38(8,9)45-33/h15,24-27,30-31H,10-14,16-23H2,1-9H3/t30-,31-/m1/s1
| StdInChIKey = OAFUHIZKKMQSAB-FIRIVFDPSA-N
}}
}}


Revision as of 17:01, 12 November 2014

O-2694
Identifiers
  • [(6aR,10aR)-6,6,9-trimethyl-3-(2-methyl-7-morpholin-4-yl-7-oxoheptan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-yl] 4-(di(propan-2-yl)amino)butanoate
PubChem CID
ChemSpider
Chemical and physical data
FormulaC38H60N2O5
Molar mass624.891 g/mol g·mol−1
3D model (JSmol)
  • O=C(N1CCOCC1)CCCCC(c3cc2OC([C@@H]4C/C=C(\C[C@H]4c2c(OC(=O)CCCN(C(C)C)C(C)C)c3)C)(C)C)(C)C
  • InChI=1S/C38H60N2O5/c1-26(2)40(27(3)4)18-12-14-35(42)44-32-24-29(37(6,7)17-11-10-13-34(41)39-19-21-43-22-20-39)25-33-36(32)30-23-28(5)15-16-31(30)38(8,9)45-33/h15,24-27,30-31H,10-14,16-23H2,1-9H3/t30-,31-/m1/s1
  • Key:OAFUHIZKKMQSAB-FIRIVFDPSA-N
  (verify)

O-2694 is a drug that is a cannabinoid derivative. It has analgesic effects and is used in scientific research. Unlike most cannabinoids discovered to date, it is highly water-soluble, which gives it considerable advantages over many related drugs. It has high affinity for both CB1 and CB2 receptors, with Ki values of 3.7nM at CB1 and 2.8nM at CB2. However, it has complex pharmacokinetics as most of the administered dose is metabolised by hydrolysis of the ester link to the water-insoluble compound O-2372, thus producing a biphasic effects profile that is less suitable for research purposes than the related compound O-2545.[1]

See also

References

  1. ^ Martin BR, et al. Pharmacological characterization of novel water-soluble cannabinoids. Journal of Pharmacology and Experimental Therapeutics. 2006 Sep;318(3):1230-9. PMID 16757541
source: https://en.wikipedia.org/w/index.php?title=O-2694&diff=prev&oldid=633545669

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