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{{Drugbox |
{{Drugbox |
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| IUPAC_name = 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone |
| IUPAC_name = 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone |
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| image = JWH-210_structure.png |
| image = JWH-210_structure.png |
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<!--Identifiers--> |
<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 824959-81-1 |
| CAS_number = 824959-81-1 |
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| CAS_supplemental = (JWH-210)<br /> 619294-47-2 (JWH-122) |
| CAS_supplemental = (JWH-210)<br /> 619294-47-2 (JWH-122) |
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Revision as of 05:04, 5 November 2011
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| Legal status |
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| Identifiers | |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.233.380 |
| Chemical and physical data | |
| Formula | C26H27NO |
| Molar mass | 369.498 g/mol g·mol−1 |
| 3D model (JSmol) | |
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JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with Ki values of 0.46nM at CB1 and 0.69nM at CB2. It is one of the most potent 4-substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity (i.e. lower Ki) at CB1 than both its 4-methyl and 4-n-propyl homologues JWH-122 (CB1 Ki 0.69nM) and JWH-182 (CB1 Ki 0.65nM) respectively, and than the 4-methoxy compound JWH-081 (CB1 Ki 1.2nM).[2] It was discovered by and named after Dr. John W. Huffman. JWH-210 and JWH-122 were banned in Sweden on 1st October 2010 as hazardous goods harmful to health, after being identified as ingredients in "herbal" synthetic cannabis products.[3][4] The substance JWH-210, JWH-122 and JWH-203 were classified as illegal drugs by the Swedish government as of 1 September, 2011.[5]
See also
References
- ^ = WDU20111050614 "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. Retrieved 12 June 2011.
{{cite web}}: Check|url=value (help) - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15582455, please use {{cite journal}} with
|pmid=15582455instead. - ^ Swedish Code of Statutes Regulation (2010:1086).
- ^ Swedish Code of Statutes Regulation (2010:1086). (pdf)
- ^ LVFS 2011:8