Cannabis Ruderalis

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'''JWH-138''' ('''THC-Octyl''', '''Δ<sup>8</sup>-THC-C8''') is a synthetic [[cannabinoid]] with a K<sub>i</sub> of 8.5nM at the CB<sub>1</sub> [[cannabinoid receptor]].<ref>Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK. Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists. ''J Pharmacol Exp Ther''. 1999 Sep;290(3):1065-79. {{pmid|10454479}}</ref><ref>{{cite patent | country = WO | number = 2020232545 | assign1 = Kare Chemical Tech Inc, Canada | inventor = Kamaluddin AR, Wenli J. Kareem AR | pubdate = 26 November 2020 | postscript = . }}</ref><ref>{{cite web | title = C-0018: THC and Related Products | url = https://www.karechem.com/_files/ugd/0b7d6c_1ca87a854b514fcca211d93900076d06.pdf | publisher = Kare Chemical Tech Inc | location = Mississauga, Ontario, Canada }}</ref>
'''JWH-138''' ('''THC-Octyl''', '''Δ<sup>8</sup>-THC-C8''') is a synthetic [[cannabinoid]] with a K<sub>i</sub> of 8.5nM at the CB<sub>1</sub> [[cannabinoid receptor]].<ref name="pmid10454479">{{cite journal | vauthors = Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK | display-authors = 6 | title = Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 290 | issue = 3 | pages = 1065–1079 | date = September 1999 | pmid = 10454479 | doi = }}</ref><ref>{{cite patent | country = WO | number = 2020232545 | assign1 = Kare Chemical Tech Inc, Canada | inventor = Kamaluddin AR, Wenli J. Kareem AR | pubdate = 26 November 2020 | postscript = . }}</ref><ref>{{cite web | title = C-0018: THC and Related Products | url = https://www.karechem.com/_files/ugd/0b7d6c_1ca87a854b514fcca211d93900076d06.pdf | publisher = Kare Chemical Tech Inc | location = Mississauga, Ontario, Canada }}</ref>


== See also ==
== See also ==

Revision as of 11:22, 21 September 2022

JWH-138
Identifiers
  • (6aR,10aR)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-octyl-6H-Dibenzo[b,d]pyran-1-ol
CAS Number
PubChem CID
Chemical and physical data
FormulaC24H36O2
Molar mass356.550 g·mol−1
3D model (JSmol)
  • OC1=C2[C@]3([C@](C(C)(C)OC2=CC(CCCCCCCC)=C1)(CCC(C)=C3)[H])[H]
  • InChI=InChI=1S/C24H36O2/c1-5-6-7-8-9-10-11-18-15-21(25)23-19-14-17(2)12-13-20(19)24(3,4)26-22(23)16-18/h14-16,19-20,25H,5-13H2,1-4H3/t19-,20-/m1/s1
  • Key:SFWRRSGOJSILSQ-WOJBJXKFSA-N

JWH-138 (THC-Octyl, Δ8-THC-C8) is a synthetic cannabinoid with a Ki of 8.5nM at the CB1 cannabinoid receptor.[1][2][3]

See also

References

  1. ^ Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, et al. (September 1999). "Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists". The Journal of Pharmacology and Experimental Therapeutics. 290 (3): 1065–1079. PMID 10454479.
  2. ^ WO 2020232545, Kamaluddin AR, Wenli J. Kareem AR, published 26 November 2020, assigned to Kare Chemical Tech Inc, Canada. 
  3. ^ "C-0018: THC and Related Products" (PDF). Mississauga, Ontario, Canada: Kare Chemical Tech Inc.


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