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| Formula | C21H30O4 |
| Molar mass | 346.467 g·mol−1 |
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Cannabitriol ((+)-CBT, (S,S)-9,10-Dihydroxy-Δ6a(10a)-THC) is a phytocannabinoid first isolated in 1966,[1][2] an oxidation product of tetrahydrocannabinol which has been identified both as a trace component of cannabis and as a metabolite in cannabis users.[3] Its pharmacology has been little studied, though it has been found to act as an anti-estrogen and aromatase inhibitor.[4][5]
See also
References
- ^ Chan WR, Magnus KE, Watson HA. The structure of cannabitriol. Experientia. 1976 Mar 15;32(3):283-4. doi:10.1007/BF01940792 PMID 1253891
- ^ Elsohly MA, El-Feraly FS, Turner CE. Isolation and characterization of (+)-cannabitriol and (-)-10-ethoxy-9-hydroxy-delta 6a[10a]-tetrahydrocannabinol: two new cannabinoids from Cannabis sativa L. extract. Lloydia. 1977 May-Jun;40(3):275-80. PMID 895385
- ^ White RM. Instability and poor recovery of cannabinoids in urine, oral fluid, and hair. Forensic Sci Rev. 2018 Jan;30(1):33-49. PMID 29273570
- ^ Baroi S, Saha A, Bachar R, Bachar S. Cannabinoid as Potential Aromatase Inhibitor Through Molecular Modeling and Screening for Anti-Cancer Activity. Dhaka University Journal of Pharmaceutical Sciences 2020; 19: 47-58. doi:10.3329/dujps.v19i1.47818
- ^ Kikiowo B, Ogunleye AJ, Iwaloye O, Ijatuyi TT, Adelakun NS, Alashe WO. Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer. Recent Pat Anticancer Drug Discov. 2021;16(2):273-284. doi:10.2174/1574892816666210201115359 PMID 33563181