Cannabis Ruderalis

CB-13
Identifiers
  • naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H24O2
Molar mass368.467 g/mol g·mol−1
3D model (JSmol)
  • c13ccccc1cccc3C(=O)c4ccc(OCCCCC)c2ccccc24

CB-13 is a cannabinoid drug, which acts as a potent agonist at both the CB1 and CB2 receptors, but does not cross the blood-brain barrier and so has only peripheral effects. It has antihyperalgesic properties in animal studies.[1]


References

  1. ^ Dziadulewicz EK, Bevan SJ, Brain CT, Coote PR, Culshaw AJ, Davis AJ, Edwards LJ, Fisher AJ, Fox AJ, Gentry C, Groarke A, Hart TW, Huber W, James IF, Kesingland A, La Vecchia L, Loong Y, Lyothier I, McNair K, O'Farrell C, Peacock M, Portmann R, Schopfer U, Yaqoob M, Zadrobilek J. Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration. Journal of Medicinal Chemistry. 2007 Aug 9;50(16):3851-6. PMID 17630726

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