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[[Category:Cannabinoids]] |
[[Category:Cannabinoids]] |
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[[Category:Designer drugs]] |
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[[Category:Naphthalenes]] |
[[Category:Naphthalenes]] |
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[[Category:Aromatic ketones]] |
[[Category:Aromatic ketones]] |
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Revision as of 02:18, 6 May 2015
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| Formula | C26H24O2 |
| Molar mass | 368.467 g/mol g·mol−1 |
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CB-13 (CRA13, SAB-378)[1] is a cannabinoid drug, which acts as a potent agonist at both the CB1 and CB2 receptors, but has poor blood–brain barrier penetration, and so produces only peripheral effects at low doses, with symptoms of central effects such as catalepsy only appearing at much higher dose ranges. It has antihyperalgesic properties in animal studies,[2] and has progressed to preliminary human trials.[3]
See also
References
- ^ Attention: This template ({{cite doi}}) is deprecated. To cite the publication identified by doi:10.1124/jpet.110.169946, please use {{cite journal}} (if it was published in a bona fide academic journal, otherwise {{cite report}} with
|doi=10.1124/jpet.110.169946instead. - ^ Template:Cite DOI
- ^ Gardin A, Kucher K, Kiese B, Appel-Dingemanse S (April 2009). "Cannabinoid receptor agonist 13, a novel cannabinoid agonist: first in human pharmacokinetics and safety". Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37 (4): 827–33. doi:10.1124/dmd.108.024000. PMID 19144772.
{{cite journal}}: CS1 maint: multiple names: authors list (link)