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| StdInChI = 1S/C24H23FN2O/c25-15-6-1-7-16-27-17-21(20-12-4-5-14-23(20)27)24(28)26-22-13-8-10-18-9-2-3-11-19(18)22/h2-5,8-14,17H,1,6-7,15-16H2,(H,26,28) |
| StdInChI = 1S/C24H23FN2O/c25-15-6-1-7-16-27-17-21(20-12-4-5-14-23(20)27)24(28)26-22-13-8-10-18-9-2-3-11-19(18)22/h2-5,8-14,17H,1,6-7,15-16H2,(H,26,28) |
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| StdInChIKey = DJKVOBZLMBHFKX-UHFFFAOYSA-N |
| StdInChIKey = DJKVOBZLMBHFKX-UHFFFAOYSA-N |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 3T22QDP4D9 |
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Revision as of 20:33, 31 March 2016
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| Formula | C24H23FN2O |
| Molar mass | 374.45 g/mol g·mol−1 |
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5F-NNE1 (also known as 5F-NNEI and 5F-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1][2] Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen.
Legality
Sweden's public health agency suggested classifying 5F-NNE1 as hazardous substance on November 10, 2014.[3]
See also
References
- ^ "5F-NNEI". Southern Association of Forensic Scientists. Retrieved 24 July 2015.
- ^ Ariane Wohlfarth, Marisol S. Castaneto, Mingshe Zhu, Shaokun Pang, Karl B. Scheidweiler, Robert Kronstrand, Marilyn A. Huestis (May 2015). "Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA". The AAPS Journal. 17 (3): 660–677. doi:10.1208/s12248-015-9721-0. PMID 25721194.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ "Cannabinoider föreslås bli klassade som hälsofarlig vara". Folkhälsomyndigheten. Retrieved 24 July 2015.