Cannabis Ruderalis

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==Related compounds==
==Related compounds==
The corresponding indole core analogue, '''4F-MDMB-BICA''' or '''4F-MDMB-BUTICA''' has also been sold as a designer drug, first being identified in May 2020.<ref>[https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/4F-MDMB-BICA-ID-HIFS-020.pdf Analytical data for 4F-MDMB-BICA. Hungarian Institute for Forensic Sciences. 28-05-2020]</ref>
The corresponding indole core analogue, '''[[4F-MDMB-BICA]]''' or '''4F-MDMB-BUTICA''' has also been sold as a designer drug, first being identified in May 2020.<ref>[https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/4F-MDMB-BICA-ID-HIFS-020.pdf Analytical data for 4F-MDMB-BICA. Hungarian Institute for Forensic Sciences. 28-05-2020]</ref>
[[Image:4F-MDMB-BICA_structure.png|180px|thumb|left|4F-MDMB-BICA]]{{clear-left}}
[[Image:4F-MDMB-BICA_structure.png|180px|thumb|left|4F-MDMB-BICA]]{{clear-left}}



Revision as of 01:31, 2 December 2020

4F-MDMB-BINACA
Legal status
Legal status
Identifiers
  • Methyl (S)-2-(1-(4-fluorobutyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate
PubChem CID
ChemSpider
Chemical and physical data
FormulaC19H26FN3O3
Molar mass363.433 g·mol−1
3D model (JSmol)
  • O=C(N[C@H](C(OC)=O)C(C)(C)C)C1=NN(CCCCF)C2=C1C=CC=C2
  • InChI=1S/C19H26FN3O3/c1-19(2,3)16(18(25)26-4)21-17(24)15-13-9-5-6-10-14(13)23(22-15)12-8-7-11-20/h5-6,9-10,16H,7-8,11-12H2,1-4H3,(H,21,24)/t16-/m1/s1
  • Key:GZGKSDAMWRWYOZ-MRXNPFEDSA-N

4F-MDMB-BINACA (also known as 4F-MDMB-BUTINACA or 4F-ADB) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family.[1] It has been used as an active ingredient in synthetic cannabis products and sold as a designer drug since late 2018. 4F-MDMB-BINACA is an agonist of the CB1 receptor (EC50 = 7.39 nM),[2] though it is unclear whether it is selective for this target.[3] In December 2019, the UNODC announced scheduling recommendations placing 4F-MDMB-BINACA into Schedule II throughout the world.[4]

Related compounds

The corresponding indole core analogue, 4F-MDMB-BICA or 4F-MDMB-BUTICA has also been sold as a designer drug, first being identified in May 2020.[5]

4F-MDMB-BICA

See also

References

  1. ^ Krotulski, Alex J.; Mohr, Amanda L. A.; Kacinko, Sherri L.; Fogarty, Melissa F.; Shuda, Sarah A.; Diamond, Francis X.; Kinney, William A.; Menendez, M. J.; Logan, Barry K. (September 2019). "4F-MDMB-BINACA: A New Synthetic Cannabinoid Widely Implicated in Forensic Casework". Journal of Forensic Sciences. 64 (5): 1451–1461. doi:10.1111/1556-4029.14101. ISSN 1556-4029. PMID 31260580. S2CID 195770459.
  2. ^ . doi:10.1021/acschemneuro.0c00644. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  3. ^ "4F-MDMB-BINACA(4F-MDMB-BUTINACA)" (PDF).
  4. ^ "December 2019 – WHO: World Health Organization recommends 12 NPS for scheduling".
  5. ^ Analytical data for 4F-MDMB-BICA. Hungarian Institute for Forensic Sciences. 28-05-2020


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