This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
Akinloye O, Gromoll J, Callies C, Nieschlag E, Simoni M (October 2007). "Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure". Andrologia. 39 (5): 190–5. doi:10.1111/j.1439-0272.2007.00789.x. PMID17714218. S2CID13317343.
Yazarloo F, Shirkoohi R, Mobasheri MB, Emami A, Modarressi MH (March 2013). "Expression analysis of four testis-specific genes AURKC, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expression pattern". Med. Oncol. 30 (1): 368. doi:10.1007/s12032-012-0368-8. PMID23292864. S2CID20377221.
Oh HR, An CH, Yoo NJ, Lee SH (July 2015). "Frameshift mutations of TAF7L gene, a core component for transcription by RNA polymerase II, in colorectal cancers". Pathol. Oncol. Res. 21 (3): 849–50. doi:10.1007/s12253-014-9832-4. PMID25098277. S2CID15595245.