The following highways are numbered 249:

• Prince Edward Island Route 249
• Quebec Route 249

• National Route 249

• Japan National Route 249

• Alabama State Route 249
• California State Route 249
• Florida State Road 249
• Georgia State Route 249 (former)
• Indiana State Road 249
• Iowa Highway 249 (former)
• K-249 (Kansas highway)
• Kentucky Route 249
• Maryland Route 249
• Minnesota State Highway 249 (former)
• Missouri Route 249
• Montana Secondary Highway 249
• New Mexico State Road 249
• New York State Route 249
• Ohio State Route 249
• Pennsylvania Route 249
• South Dakota Highway 249
• Tennessee State Route 249
• Texas State Highway 249
  • Farm to Market Road 249 (Texas)
• Utah State Route 249 (former)
• Virginia State Route 249