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ECHA InfoCard | 100.037.140 |
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Formula | C42H69NO15 |
Molar mass | 828.006 g·mol−1 |
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Josamycin is a macrolide antibiotic. It was isolated by Hamao Umezawa and his colleagues from strains of Streptomyces narbonensis var. josamyceticus var. nova in 1964.[1][2]
It is currently sold in various countries.Brand examples are:
- Europe: Josalid, Josacine, Iosalide, Josamina
- Russia: Wilprafen (Вильпрафен)
- Japan: Josamy
Adverse effects
[edit]There has been a case report of edema of the feet.[3]
References
[edit]- ^ Osono T, Oka Y, Watanabe S, Okami Y, Umezawa H (July 1967). "A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristics". The Journal of Antibiotics. 20 (3): 174–180. PMID 6072798.
- ^ Umezawa H (1982). "Discovery of josamycin". Giornale Italiano di Chemioterapia. 29 (Suppl 1): 1–10. PMID 6765367.
- ^ Bosch X, Pedrol E, Casado X, Urbano-Marquez A (July 1993). "Josamycin-induced pedal oedema". BMJ. 307 (6895): 26. doi:10.1136/bmj.307.6895.26-a. PMC 1678472. PMID 8343666.