John McDermott may refer to:

• John McDermott (boxer) (born 1980), British boxer
• John McDermott (English footballer) (born 1969), former Grimsby Town footballer
• John McDermott (Gaelic footballer), former Meath Gaelic footballer
• John McDermott (director) (1893–1946), American film director and screenwriter
• John McDermott (Australian footballer) (1872–1925), Australian rules footballer
• John McDermott (golfer) (1891–1971), American golfer
• John McDermott (American artist) (1919–1977), American illustrator and author
• John McDermott (runner) (1880–1948), American marathoner
• John McDermott (singer) (born 1955), Scottish-Canadian singer
• John F. McDermott, American psychiatrist
• John J. McDermott (philosopher) (1932–2018), distinguished professor at Texas A&M University
• John McDermott (Scottish artist) (born 1957), Scottish artist and veteran affairs activist

• Jack McDermott (1906–1958), Irish trade unionist
• John MacDermott (disambiguation)