Relaxin/insulin-like family peptide receptor 2

RXFP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRXFP2, GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2, Relaxin/insulin-like family peptide receptor 2, relaxin/insulin like family peptide receptor 2, relaxin family peptide receptor 2
External IDsOMIM: 606655 MGI: 2153463 HomoloGene: 15402 GeneCards: RXFP2
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for RXFP2
Genomic location for RXFP2
Band13q13.1Start31,739,526 bp[1]
End31,803,389 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001166058
NM_130806

NM_001289564
NM_001289566
NM_080468

RefSeq (protein)

NP_001159530
NP_570718

NP_001276493
NP_001276495
NP_536716

Location (UCSC)Chr 13: 31.74 – 31.8 MbChr 5: 150.02 – 150.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Relaxin/insulin-like family peptide receptor 2, also known as RXFP2, is a human G-protein coupled receptor.[5]

The receptors for glycoprotein hormones such as follicle-stimulating hormone (FSH; see MIM 136530) and thyroid-stimulating hormone (TSH; see MIM 188540) are G protein-coupled, 7-transmembrane receptors (GPCRs) with large N-terminal extracellular domains. Leucine-rich repeat (LRR)-containing GPCRs (LGRs) form a subgroup of the GPCR superfamily.[supplied by OMIM][5]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133105 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053368 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: RXFP2 relaxin/insulin-like family peptide receptor 2".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.