NMP-7 structure.png
CAS Number
PubChem CID
Chemical and physical data
Molar mass348.490 g·mol−1
3D model (JSmol)

NMP-7 is a drug which acts as both a non-selective agonist of the CB1 and CB2 cannabinoid receptors, and also as a blocker of T-type calcium channels, the target of anticonvulsant drugs such as ethosuximide. NMP-7 has an agonist EC50 of 96.9nM at CB1 and 10.5nM at CB2, and an IC50 of 1.84μM for blocking Cav3.2 T-type calcium channels. In animal studies it produces potent analgesic effects in a variety of different tests.[1]

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  1. ^ You H, Gadotti VM, Petrov RR, Zamponi GW, Diaz P (November 2011). "Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands". Molecular Pain. 7: 1744-8069–7-89. doi:10.1186/1744-8069-7-89. PMC 3250956. PMID 22093952.