Cannabis Sativa

HU-345
Identifiers
	IUPAC name 6,6,9-Trimethyl-3-pentyl-1H-benzo[c]chromene-1,4(6H)-dione;
PubChem CID	11198119;
ChemSpider	9373188 ;
ChEMBL	ChEMBL127671 ;
Chemical and physical data
Formula	C21H24O3
Molar mass	324.414 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2\C(=C/C(=O)C=3c1c(ccc(c1)C)C(OC2=3)(C)C)CCCCC;
	InChI InChI=1S/C21H24O3/c1-5-6-7-8-14-12-17(22)18-15-11-13(2)9-10-16(15)21(3,4)24-20(18)19(14)23/h9-12H,5-8H2,1-4H3 ; Key:UFDYTRQMIXJHTH-UHFFFAOYSA-N ;
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HU-345 (cannabinol quinone) is a drug that is able to inhibit aortic ring angiogenesis more potently than its parent compound cannabinol.^[1]^[2]

References[edit]

^ Kogan NM, Blázquez C, Alvarez L, Gallily R, Schlesinger M, Guzmán M, Mechoulam R (July 2006). "A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells". Molecular Pharmacology. 70 (1): 51–9. doi:10.1124/mol.105.021089. PMID 16571653.
^ US patent 0092584, Mechoulam R, Kogan NM, Rabinowitz R, Schlesinger M, "Therapeutic Use of Quinonoid Derivatives of Cannabinoids", granted 2011-04-21

Identifiers

IUPAC name 6,6,9-Trimethyl-3-pentyl-1H-benzo[c]chromene-1,4(6H)-dione
PubChem CID	11198119
ChemSpider	9373188^Y
ChEMBL	ChEMBL127671^Y
Chemical and physical data
Formula	C₂₁H₂₄O₃
Molar mass	324.414 g/mol g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C2\C(=C/C(=O)C=3c1c(ccc(c1)C)C(OC2=3)(C)C)CCCCC
InChI InChI=1S/C21H24O3/c1-5-6-7-8-14-12-17(22)18-15-11-13(2)9-10-16(15)21(3,4)24-20(18)19(14)23/h9-12H,5-8H2,1-4H3^Y Key:UFDYTRQMIXJHTH-UHFFFAOYSA-N^Y
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