SLC37A1
Identifiers
Aliases	SLC37A1, G3PP, solute carrier family 37 member 1
External IDs	OMIM: 608094 MGI: 2446181 HomoloGene: 70486 GeneCards: SLC37A1
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.3 Start 42,496,008 bp[1] End 42,581,440 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B1 Start 31,505,766 bp[2] End 31,569,713 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Top expressed in More reference expression data BioGPS n/a
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54020 224674 Ensembl ENSG00000160190 ENSMUSG00000024036 UniProt P57057 Q8R070 RefSeq (mRNA) NM_018964 NM_001320537 NM_001242427 NM_153062 RefSeq (protein) NP_001307466 NP_061837 NP_001229356 NP_694702 Location (UCSC) Chr 21: 42.5 – 42.58 Mb Chr 17: 31.51 – 31.57 Mb PubMed search [3] [4]
Wikidata
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Glucose-6-phosphate exchanger SLC37A1 is a protein that in humans is encoded by the SLC37A1 gene.^[5] SLC37A1 locates to the membrane of the endoplasmic reticulum (ER), and is a glucose 6-phosphate:inorganic phosphate antiporter, transporting glucose 6-phosphate from the cytoplasm into the lumen of the ER, while transporting phosphate in the opposite direction.^[6]

Unlike the related SLC37A4 protein, SLC37A1 does not appear to be involved in blood glucose homeostasis,^[7] but does appear to regulate phosphate levels in the milk of cows, with flow-on effects on the volume of milk produced.^[8]

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