Alphenal ball-and-stick animation.gif
Clinical data
Synonyms 5-Phenyl-5-allylbarbituric acid
Routes of
ATC code
  • none
Legal status
Legal status
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard 100.003.718 Edit this at Wikidata
Chemical and physical data
Formula C13H12N2O3
Molar mass 244.246 g/mol g·mol−1
3D model (JSmol)

Alphenal (Alphenal, Efrodal, Prophenal, Sanudorm), also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s.[1] It has primarily anticonvulsant properties, and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly as better known barbiturates such as phenobarbital.[2][3]

LD50: Mouse (Oral): 280 mg/kg


  1. ^ DE Patent 526854
  2. ^ Carissimi M, Nuovi Barbiturici Alogenati. Farmaco. Ediozione scientifica. 17(6):390-413. (1962).
  3. ^ Martin, J. R.; Godel, T.; Hunkeler, W.; Jenck, F.; Moreau, J.-L.; Sleight, A. J.; Widmer, U. (2000). “Psychopharmacological Agents”. doi:10.1002/0471238961.1619250313011820.a01.
  4. ^ Hans Brandenberger; Robert A. A. Maes (1997). Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists. Walter de Gruyter. p. 348. ISBN 978-3-11-010731-9. Retrieved 19 May 2012.
  5. ^ Pelayo Camps García; Santiago Vázquez Cruz; Carmen Escolano Mirón (28 January 2005). Fundamentos de síntesis de fármacos. Edicions Universitat Barcelona. p. 161. ISBN 978-84-475-2876-9. Retrieved 19 May 2012.