The score was tied in the sixth when Mickey Mantle and Killebrew singled and scored on a Brooks Robinson triple to right-center. The AL regained the lead 4–3 in the seventh. Elston Howard was hit by a pitch by Turk Farrell, took third on a Rocky Colavito double and scored on Fregosi's sacrifice fly.
It remained 4–3 until the bottom of the ninth. Dick Radatz issued a leadoff walk to Willie Mays, who stole second. Orlando Cepeda singled him home with the tying run and took second on an error. With Curt Flood pinch-running for Cepeda and Johnny Edwards on first with an intentional walk, Johnny Callison's three-run homer to deep right field ended the game.