Hermione may refer to:
- People
- Hermione (given name), a female given name
- Hermione (mythology), only daughter of Menelaus and Helen in Greek mythology and original bearer of the name
- Hermione Gingold, actress
- Arts and Literature
- Cadmus et Hermione, an opera by Jean-Baptiste Lully
- Hermione, a character in Shakespeare's The Winter's Tale
- HERmione, a novel by American poet, Hilda "H.D." Doolittle
- Hermione Granger, a main character in the Harry Potter novels and films
- Letter to Hermione, a song from the album Space Oddity by David Bowie
- Ships
- French ship Hermione, twelve ships of the French Navy
- French frigate Hermione (1779), a French frigate that carried La Fayette to join the American fight for independence in 1780
- French frigate Hermione (2014), a replica of the 1779 original, built in France from 1996 to 2012, launched in 2014.
- HMS Hermione, four ships of the Royal Navy, the crew of the first of which mutinied, killing the captain and most of the officers before handing the ship over to the enemy.
- Spanish frigate Hermione, captured by the British Navy with a notably valuable cargo in the action of 31 May 1762.
- Other uses
- 121 Hermione, an asteroid
- Epiphryne (syn. Hermione), a genus of moth in the family Geometridae
- Ermioni, a resort town in Greece originally called Hermione
- Hermione (Tallulah, Louisiana), a Greek Revival building built in 1855 in Tallulah, Louisiana
- Hermiones, The Irminones, a group of early Germanic tribes
- Hotspot Ecosystem Research and Man's Impact On European Seas (HERMIONE), an EU-funded deep-sea research project
- Sony Ericsson P990, a mobile phone codenamed Hermione
- USS Hawk (IX-14), formerly called Hermione