Shadowrun is a pen and paper role-playing game, first released in 1989.

Shadowrun may also refer to:

• Video games based on the role-playing game:
  • Shadowrun (SNES), a 1993 game for the Super NES
  • Shadowrun (Sega), a 1994 game for the Sega Genesis
  • Shadowrun (Mega-CD), a 1996 game for the Sega Mega-CD
  • Shadowrun (2007 video game), for the Xbox 360 and Windows Vista
  • Shadowrun Returns, a 2013 game for Windows, Mac and Linux PCs.
• Shadowrun: The Trading Card Game, a 1997 collectible card game

• Other uses:
  • The Shadow Run, a 1990 crime novel unrelated to the games (ISBN 0749302976)
  • Shadow Run (film), a 1998 crime film based on the novel The Shadow Run