Authors
Giorgio Gandaglia, Guillaume Ploussard, Massimo Valerio, Agostino Mattei, Cristian Fiori, Mathieu Roumiguié, Nicola Fossati, Armando Stabile, Jean-Baptiste Beauval, Bernard Malavaud, Simone Scuderi, Francesco Barletta, Marco Moschini, Stefania Zamboni, Arnas Rakauskas, Zhe Tian, Pierre I Karakiewicz, Francesco De Cobelli, Francesco Porpiglia, Francesco Montorsi, Alberto Briganti
Publication date
2020/6/1
Journal
European urology
Volume
77
Issue
6
Pages
733-741
Publisher
Elsevier
Description
Background
The combined role of multiparametric magnetic resonance imaging (mp-MRI), and magnetic resonance imaging (MRI)-targeted and concomitant systematic biopsies in the identification of prostate cancer (PCa) patients at a higher risk of adverse pathology at radical prostatectomy (RP) is still unclear.
Objective
To develop novel models to predict extracapsular extension (ECE), seminal vesicle invasion (SVI), or upgrading in patients diagnosed with MRI-targeted and concomitant systematic biopsies.
Design, setting, and participants
We included 614 men with clinical stage ≤ T2 at digital rectal examination who underwent MRI-targeted biopsy with concomitant systematic biopsy.
Outcome measurements and statistical analyses
Logistic regression analyses predicting ECE, SVI, and upgrading (ie, a shift from biopsy International Society of Urological Pathology grade group to any higher grade at RP) based on …
Scholar articles
G Gandaglia, G Ploussard, M Valerio, A Mattei, C Fiori… - European urology, 2020