TGFβ–SMAD signal transduction: molecular specificity and functional flexibility B Schmierer, CS Hill Nature reviews Molecular cell biology 8 (12), 970-982, 2007 | 1611 | 2007 |
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response E Haapaniemi, S Botla, J Persson, B Schmierer, J Taipale Nature medicine 24 (7), 927-930, 2018 | 1133 | 2018 |
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ... Cell 154 (4), 801-813, 2013 | 384 | 2013 |
Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor β-dependent nuclear accumulation of Smads B Schmierer, CS Hill Molecular and cellular biology, 2005 | 256 | 2005 |
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system B Schmierer, AL Tournier, PA Bates, CS Hill Proceedings of the National Academy of Sciences 105 (18), 6608-6613, 2008 | 243 | 2008 |
Analysis of Smad nucleocytoplasmic shuttling in living cells FJ Nicolás, K De Bosscher, B Schmierer, CS Hill Journal of cell science 117 (18), 4113-4125, 2004 | 183 | 2004 |
Bleeding risk of surgery and its prevention in patients with inherited platelet disorders S Orsini, P Noris, L Bury, PG Heller, C Santoro, RA Kadir, NC Butta, ... haematologica 102 (7), 1192, 2017 | 120 | 2017 |
Catecholamines up‐regulate lipopolysaccharide‐induced IL‐6 production in human microvascular endothelial cells A Gornikiewicz, T Sautner, C Brostjan, B Schmierer, R Függer, E Roth, ... The FASEB Journal 14 (9), 1093-1100, 2000 | 110 | 2000 |
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-β/Activin/Nodal signalling J Batut, B Schmierer, J Cao, LA Raftery, CS Hill, M Howell Oxford University Press for The Company of Biologists Limited 135 (17), 2927 …, 2008 | 105 | 2008 |
Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-{beta} Pathway P Vizan, DSJ Miller, I Gori, D Das, B Schmierer, CS Hill Science Signaling 6 (305), ra106, 2013 | 84 | 2013 |
Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor M Yang, W Ge, R Chowdhury, TDW Claridge, HB Kramer, B Schmierer, ... Journal of biological chemistry 286 (9), 7648-7660, 2011 | 84 | 2011 |
CRISPR/Cas9 screening using unique molecular identifiers B Schmierer, SK Botla, J Zhang, M Turunen, T Kivioja, J Taipale Molecular systems biology 13 (10), 945, 2017 | 65 | 2017 |
Structural insights into the DNA-binding specificity of E2F family transcription factors E Morgunova, Y Yin, A Jolma, K Dave, B Schmierer, A Popov, N Eremina, ... Nature communications 6 (1), 10050, 2015 | 64 | 2015 |
Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response-a predictive kinetic model B Schmierer, B Novák, CJ Schofield BMC systems biology 4, 1-17, 2010 | 51 | 2010 |
Activin A and follicle-stimulating hormone control tight junctions in avian granulosa cells by regulating occludin expression MK Schuster, B Schmierer, A Shkumatava, K Kuchler Biology of Reproduction 70 (5), 1493-1499, 2004 | 50 | 2004 |
TGF-β family ligands exhibit distinct signalling dynamics that are driven by receptor localisation DSJ Miller, B Schmierer, CS Hill Journal of cell science 132 (14), jcs234039, 2019 | 36 | 2019 |
Contribution of allelic imbalance to colorectal cancer K Palin, E Pitkänen, M Turunen, B Sahu, P Pihlajamaa, T Kivioja, ... Nature communications 9 (1), 3664, 2018 | 34 | 2018 |
Endothelial cells downregulate expression of the 70 kDa heat shock protein during hypoxia R Oehler, B Schmierer, M Zellner, R Prohaska, E Roth Biochemical and biophysical research communications 274 (2), 542-547, 2000 | 33 | 2000 |
Activin a signaling induces Smad2, but not Smad3, requiring protein kinase a activity in granulosa cells from the avian ovary B Schmierer, MK Schuster, A Shkumatava, K Kuchler Journal of Biological Chemistry 278 (23), 21197-21203, 2003 | 32 | 2003 |
Upregulation of chicken p15INK4b at senescence and in the developing brain SH Kim, J Rowe, H Fujii, R Jones, B Schmierer, BW Kong, K Kuchler, ... Journal of cell science 119 (12), 2435-2443, 2006 | 31 | 2006 |