A starbase, in science fiction, is a facility in space.
Starbase or variation, may also refer to:
- STARBASE, a math and science educational program for students
- StarBase, a StarOffice database application
- StarBase (biological database), an RNA database
- Starbase 12, a starbase in the video game Star Trek: Bridge Commander
- SpaceX Starbase, a spaceport located at Boca Chica, Texas, United States
- Starbase (video game), a space themed multiplayer video game
- Starbase, a proprietary graphics API for HP-UX