Maria Luisa may refer to:
People[edit]
- Anna Maria Luisa de' Medici (1667–1743), last lineal descent of the House of Medici
- Maria Luisa Ambrosini (20th century), non-fiction author
- Maria Luisa, Duchess of Lucca (1782–1824), Queen of Etruria
- María Luisa Elío (1926–2009), Spanish writer and actress
- María Luisa Gil (born 1977), Cuban model and actress
- María Luisa Josefa (1866–1937), Mexican Roman Catholic nun
- Maria Luisa of Orléans (1662–1689), Queen consort of Spain
- Maria Luisa of Parma (1751–1819), Queen consort of Spain
- Maria Luisa of Savoy (1688–1714), Queen consort of Spain
- Maria Luisa Spaziani (1923–2014), Italian poet
- María Luisa Zea (1913–2002), Mexican actress and singer
Places[edit]
- Aldea María Luisa, town in Entre Ríos Province, Argentina
- María Luisa, Argentina, town in Santa Fe Province, Argentina
Ships[edit]
- SS Maria Luisa, a number of ships with this name