Route 440 or Highway 440 may refer to:

Australia[edit]

• South Gippsland Highway

Canada[edit]

• Manitoba Provincial Road 440
• New Brunswick Route 440
• Newfoundland and Labrador Route 440
• Quebec Autoroute 440

Japan[edit]

• Route 440 (Japan)

United States[edit]

• Interstate 440 (disambiguation)
• Arkansas Highway 440
• Hawaii Route 440
• Louisiana Highway 440
• Maryland Route 440
• New Jersey Route 440
• New York State Route 440
• Ohio State Route 440 (former)
• Puerto Rico Highway 440