The following highways are numbered 376:

Canada[edit]

• Nova Scotia Route 376
• Saskatchewan Highway 376

Japan[edit]

• Japan National Route 376

United States[edit]

• Interstate 376
• Interstate 376 Business Loop
• Florida State Road 376 (former)
• Georgia State Route 376
• Iowa Highway 376 (unsigned designation for US 75 Bus.)
• Maryland Route 376
• Missouri Route 376
• Montana Secondary Highway 376 (former)
• Nevada State Route 376
• New York State Route 376
• Ohio State Route 376
• Puerto Rico Highway 376
• Virginia State Route 376
• Wyoming Highway 376