Histone cluster 2 H3 family member d is a protein that in humans is encoded by the HIST2H3D gene. [5]
Function[edit]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. [provided by RefSeq, Aug 2015].
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000183598 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000069310 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Histone cluster 2 H3 family member d". Retrieved 2018-05-17.
Further reading[edit]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.