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Summary
| Description |
English: Vitamin B12 total syntheses (Harvard/ETH A/B approach to cobyric acid): Coupling of the Harvard f-differentiated A-D-component with the ETH B-C-component, leading to the "common corrinoid intermediate", a 5,15-bisnor-cobyrinate bearing a nitrile group at the ring-D f-propionic acid side chain, and ester groups at all other acetic and propionic acid side chains. Key steps in the coupling and following A/D corrin ring closure are two variants of the Eschenmoser sulfide contraction |
| Date | |
| Source | Own work |
| Author | Easyloc |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 09:53, 25 December 2019 | | 711 × 1,122 (332 KB) | Easyloc | User created page with UploadWizard |
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