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FCMR
Identifiers
Aliases	FCMR, TOSO, FAIM3, Fc fragment of IgM receptor, Fc mu receptor, FcmuR
External IDs	OMIM: 606015 MGI: 1916419 HomoloGene: 48347 GeneCards: FCMR
Gene location (Human)
Chr.	Chromosome 1 (human)
End	206,923,247 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	130,808,528 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Orthologs
	9214
	69169
	ENSG00000162894
	ENSMUSG00000042474
	O60667
	A1KXC4
	NM_001142472; NM_001142473; NM_001193338; NM_005449
	NM_026976
	NP_001135945; NP_001180267; NP_005440
	NP_081252; NP_001392822
	Wikidata
View/Edit Human	View/Edit Mouse

Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene. ^[5]

Function[edit]

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162894 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042474 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Fc fragment of IgM receptor". Retrieved 2016-03-24.

Further reading[edit]

Sigruener A, Buechler C, Bared SM, Grandl M, Aslanidis C, Ugocsai P, Gehrmann M, Schmitz G (2007). "E-LDL upregulates TOSO expression and enhances the survival of human macrophages". Biochem. Biophys. Res. Commun. 359 (3): 723–8. doi:10.1016/j.bbrc.2007.05.169. PMID 17553462.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162894 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042474 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Fc fragment of IgM receptor". Retrieved 2016-03-24.

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Function[edit]

References[edit]

Further reading[edit]

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