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Catherine E. Costello
Alma materGeorgetown University
Scientific career
InstitutionsBoston University School of Medicine
ThesisElectrophilic brominations of poly-substituted olefins; reactions and NMR studies (1971)

Catherine E. Costello is the William Fairfield Warren distinguished professor in the department of biochemistry, Cell Biology and Genomics, and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine.[1]

Education[edit]

Catherine E. Costello attended the Emmanuel College in Boston for her undergraduate studies in chemistry, and minors in mathematics and physics.[2] She received a Master of Science (1967) and a PhD from Georgetown University (1971).[3][4] After graduation, she did post-doctoral research with Klaus Biemann at Massachusetts Institute of Technology.

Career[edit]

Prior to founding the Center for Biomedical Mass Spectrometry at Boston University School of Medicine in 1994, Costello was a senior research scientist and the associate director of the National Institutes of Health Research Resource for Mass Spectrometry at Massachusetts Institute of Technology for 20 years.[5][6] She is a William Fairfield Warren Distinguished Professor and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine.[5][7]

Costello served as the president of the American Society for Mass Spectrometry (2002–2004),[8] the Human Proteome Organization (2011–2012),[9] and the International Mass Spectrometry Foundation (2014–2018).[10] She currently serves on the board of directors of the US Human Proteome Organization,[11] and the editorial board of Clinical Proteomics.[12]

Research[edit]

Her research involves structural characterization of biopolymers using mass spectrometry-based techniques, such as liquid chromatography-mass spectrometry, thin-layer chromatography-mass spectrometry, Fourier-transform ion cyclotron resonance mass spectrometry, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, microfluidic capillary electrophoresis-mass spectrometry, and ion mobility spectrometry-mass spectrometry.[7][13] She was one of the first scientists to characterize glycoconjugates with tandem mass spectrometry.[6] Her 1988 article has been cited over two thousand times.[14] She participated in the Human Proteome Project,[15] the SysteMHC Atlas project,[16] and the Minimum Information Required for a Glycomics Experiment (MIRAGE) project.[17]

Awards[edit]

Awards in her honor[edit]

  • US Human Proteome Organization Catherine E. Costello Lifetime Achievement in Proteomics Award (from 2020)[22]
  • Females in Mass Spectrometry Catherine E. Costello Award (from 2020)[35]

References[edit]

  1. ^ "Boston University Profile".
  2. ^ Bhattacharya, Nivedita (2018). "Pioneering women in mass spectrometry – an interview with Catherine E. Costello". Rapid Communications in Mass Spectrometry. 32 (8): 607–611. Bibcode:2018RCMS...32..607B. doi:10.1002/rcm.8078. ISSN 1097-0231. PMID 29419936.
  3. ^ "Bromination reactions of selected terpenes and cholesterol". Georgetown University Library. Archived from the original on 2021-11-08. Retrieved 2021-11-08.
  4. ^ "Electrophilic brominations of poly-substituted olefins; reactions and NMR studies". Georgetown University Library. Archived from the original on 2021-11-08. Retrieved 2021-11-08.
  5. ^ a b "Catherine E. Costello, Director | Mass Spectrometry Resource". www.bumc.bu.edu. Retrieved 2021-11-07.
  6. ^ a b c "MCP_2020 Award Winner". www.glycobiology.org. Retrieved 2021-11-07.
  7. ^ a b "Catherine E. Costello | Biochemistry". www.bumc.bu.edu. Retrieved 2021-11-07.
  8. ^ "Past Presidents". www.asms.org. Retrieved 2021-11-07.
  9. ^ "HUPOST The newsletter of the Human Proteome Organisation" (PDF). Human Proteome Organization. Archived (PDF) from the original on 2020-09-20. Retrieved November 6, 2021.
  10. ^ "MSACL 2020 US : Costello". www.msacl.org. Retrieved 2021-11-07.
  11. ^ "US HUPO – Board of Directors". www.ushupo.org. Retrieved 2021-11-07.
  12. ^ "Clinical Proteomics". Clinical Proteomics. Retrieved 2021-11-07.
  13. ^ "costello ce – Search Results – PubMed". PubMed. Retrieved 2021-11-08.
  14. ^ Domon, Bruno; Costello, Catherine E. (1988-12-01). "A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates". Glycoconjugate Journal. 5 (4): 397–409. doi:10.1007/BF01049915. ISSN 1573-4986. S2CID 206787925.
  15. ^ Legrain, P.; Aebersold, R.; Archakov, A.; Bairoch, A.; Bala, K.; Beretta, L.; Bergeron, J.; Borchers, C.; Corthals, G. L.; Costello, C. E.; Deutsch, E. W. (2011-04-29). "The human proteome project: Current state and future direction". Molecular & Cellular Proteomics: O111.009993. doi:10.1074/mcp.O111.009993. ISSN 1535-9476. PMID 21531903.
  16. ^ Shao, Wenguang; Pedrioli, Patrick G A; Wolski, Witold; Scurtescu, Cristian; Schmid, Emanuel; Vizcaíno, Juan A; Courcelles, Mathieu; Schuster, Heiko; Kowalewski, Daniel; Marino, Fabio; Arlehamn, Cecilia S L (2018-01-04). "The SysteMHC Atlas project". Nucleic Acids Research. 46 (D1): D1237–D1247. doi:10.1093/nar/gkx664. ISSN 0305-1048. PMC 5753376. PMID 28985418.
  17. ^ Campbell, Matthew P; Abrahams, Jodie L; Rapp, Erdmann; Struwe, Weston B; Costello, Catherine E; Novotny, Milos; Ranzinger, Rene; York, William S; Kolarich, Daniel; Rudd, Pauline M; Kettner, Carsten (2019-05-01). "The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines". Glycobiology. 29 (5): 349–354. doi:10.1093/glycob/cwz009. ISSN 1460-2423. PMID 30778580.
  18. ^ "The Power List 2023". The Analytical Scientist. 2023-09-10. Retrieved 2023-09-02.
  19. ^ "Society for Glycobiology Awards—2020". Glycobiology. 30 (12): 936–940. 2020-12-09. doi:10.1093/glycob/cwaa088. ISSN 1460-2423. PMID 33080621.
  20. ^ "Glycobiology society honors; NAI inducts Batzer; inspiring Latinx scientists". www.asbmb.org. Retrieved 2021-11-07.
  21. ^ "BU's Catherine Costello receives Lifetime Achievement in Proteomics Award". EurekAlert!. Retrieved 2021-11-07.
  22. ^ a b "US HUPO – Lifetime Achievement Award". www.ushupo.org. Retrieved 2021-11-07.
  23. ^ "Catherine Costello Receives Lifetime Achievement in Proteomics Award | School of Medicine". www.bumc.bu.edu. Retrieved 2021-11-07.
  24. ^ "BU's Catherine Costello receives Lifetime Achievement in Proteomics Award". SCIENMAG: Latest Science and Health News. 2019-03-11. Retrieved 2021-11-07.
  25. ^ "Catherine Costello". The Analytical Scientist. Retrieved 2021-11-07.
  26. ^ "John B. Fenn Distinguished Contribution". www.asms.org. Retrieved 2021-11-07.
  27. ^ Zaia, Joseph; Bierbaum, Veronica M. (2018-06-01). "Focus on Mass Spectrometry in Glycobiology and Related Fields, Honoring Catherine E. Costello, Recipient of the 2017 ASMS Award for a Distinguished Contribution in Mass Spectrometry". Journal of the American Society for Mass Spectrometry. 29 (6): 1061–1064. Bibcode:2018JASMS..29.1061Z. doi:10.1007/s13361-018-1957-3. ISSN 1879-1123. PMID 29855889. S2CID 46920892.
  28. ^ "2016 Fellows | American Association for the Advancement of Science". www.aaas.org. Retrieved 2021-11-07.
  29. ^ a b "HUPO – Past Award Recipients". www.hupo.org. Retrieved 2021-11-07.
  30. ^ Ludwig-Gross, Michaela. "Wolfgang-Paul-Lecture". DGMS (in German). Retrieved 2022-12-27.
  31. ^ "William Fairfield Warren Distinguished Professorship | Office of the Provost". www.bu.edu. Retrieved 2021-11-07.
  32. ^ "2011 ACS Fellows". American Chemical Society. Retrieved 2021-11-07.
  33. ^ "Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry". American Chemical Society. Retrieved 2021-11-07.
  34. ^ "Thomson Medal Award | IMSC 2021" (in Brazilian Portuguese). 2019-08-30. Retrieved 2021-11-07.
  35. ^ "Catherine E. Costello Award". Females in Mass Spectrometry. 2020-07-12. Retrieved 2021-11-07.

External links[edit]

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