American Century is a term used by some historians to refer to the 20th Century.

American Century may also refer to:

• American Century (comics), a comic series published by DC Comics from 2001
• American Century Investments, an investment management firm
• The American Century: Varieties of Culture in Modern Times, a book by Norman F. Cantor
• American Century Records, a fictional record company in the TV series Vinyl
• MV American Century, a lake freighter on the Great Lakes