|ShortSummary = Whilst walking about the hospital, Chanel is attacked by the Green Meanie, but is saved by Chanel #8. Cassidy tries to kill Chanel #3, but cannot bring himself to do so, exclaiming that he didn't want to kill anymore and decides to confront his mother. Cassidy then tells Hoffel that he's out, only to be threatened by her as a response. Hester and Brock devise a plan to steal Munsch's money and buy Blood Island. Meanwhile, Hoffel takes some barrels outside, when she finds Chanel #8, who then tells her the humus in the swamp water is highly flammable, which gives Hoffel the idea to make a fertilizer bomb. As a part of Hester and Brocks plan, Brock proposes to Munsch, which upsets Chanel but Brock tells her that once Munsch is dead he will propose to Chanel. Chanel #3 and Cassidy talk to Jane, who then exclaims that Cassidy is dead to her. Meanwhile, Chanel #5 tells Munch that she might not have Kuru but the only way to find out is to have an open-brain surgery, to which Brock agrees. Hoffel starts draining the swamp of its flammable humus but unplugs the cryo chamber holding Denise (to which she didn't know). Meanwhile, Jane is feeding Zayday and expresses her sadness to her. Zayday convinces her that she is not a bad mother and killing people is not the answer. The surgery is complete and Chanel #5 reveals to Munsch that they found no evidence of Kuru in her, but she is just extremely dehydrated due to the fact that the only liquids she has consumed for a year are vodka and neat scotch. Hoffel then leads #8, Brock, Cassidy, Munsch, #3, #5, and Chanel into a trap in the basement then revealing that Chanel killed her sister to everyone. Jane and Zayday come to reason with Hoffel, who is unfazed and fatally shoots Jane. Hoffel then leaves everyone to die from the bomb. Denise revives and defuses the bomb. Everyone chases Hoffel, who kills Cassidy in the process. Hoffel falls into some quicksand and begins sinking to her death, and everyone lets her die. In the epilogue, Chanel narrates and reveals what happened to everybody after the murders. Brock and Hester steal Munsch's money, buy Blood Island, and kill every tourist there. Munsch sells the hospital and starts a sex class for women over 50. Chanel #5 and Zayday still work at the C.U.R.E. Institute and are considered the hospital's top team. Meanwhile, #3 is a manager/executive producer for Chanel's new doctor show, "Lovin' The C". At the end, Chanel is shown leaving the building and entering her car. She sees a mysteriously appearing KKT ring, from her college years, and then looks in the mirror to see the Red Devil behind her. Scream Queens in majorly believed to be referenced in Ryan Murphy’s other famous TV Series “American Horror Story.” In American Horror Story: Cult, you can spot a sign that says, “Drain the Swamp” on a poster in the first episode,“Election Night.” Many people have disregarded this sign as claiming the sign to just a part of Donald Trump’s presidential campaign while other fans of both Scream Queens and American Horror Story believe that the connection between the 2 shows in physically made by the name of the Scream Queens Season 2 finale being named “Drain the Swamp” and then spotting a sign harboring the same words within a show created by the same man.