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The human affectome
Over the last decades, theoretical perspectives in the interdisciplinary field of the
affective sciences have proliferated rather than converged due to differing
assumptions about what human affective phenomena are and how they work. These …
affective sciences have proliferated rather than converged due to differing
assumptions about what human affective phenomena are and how they work. These …
Cognitive rehabilitation for improving cognitive functions and reducing the severity of depressive symptoms in adult patients with Major Depressive Disorder: a …
Introduction Nearly 40% of patients with Major Depressive Disorder (MDD) have
been found to experience cognitive impairment in at least one domain. Cognitive
impairment associated with MDD is disproportionately represented in patients that …
been found to experience cognitive impairment in at least one domain. Cognitive
impairment associated with MDD is disproportionately represented in patients that …
Agomelatine: a potential multitarget compound for neurodevelopmental disorders
Agomelatine (AGM) is one of the latest atypical antidepressants, prescribed
exclusively for the treatment of depression in adults. AGM belongs to the
pharmaceutical class of melatonin agonist and selective serotonin antagonist …
exclusively for the treatment of depression in adults. AGM belongs to the
pharmaceutical class of melatonin agonist and selective serotonin antagonist …
Functional connectivity mapping for rTMS target selection in depression
Objective: Repetitive transcranial magnetic stimulation (rTMS) protocols increasingly
use subgenual anterior cingulate cortex (sgACC) functional connectivity to
individualize treatment targets. However, the efficacy of this approach is unclear, with …
use subgenual anterior cingulate cortex (sgACC) functional connectivity to
individualize treatment targets. However, the efficacy of this approach is unclear, with …
Hippocampus links perceived social support with self-esteem
Self-esteem is an important psychological resource with adaptive values, and
numerous investigations have revealed that self-esteem is influenced by perceived
social support. However, the potential neural basis linking perceived social support …
numerous investigations have revealed that self-esteem is influenced by perceived
social support. However, the potential neural basis linking perceived social support …
Novel mechanism-based treatments for pediatric anxiety and depressive disorders
Pediatric anxiety and depressive disorders are common, can be highly impairing,
and can persist despite the best available treatments. Here, we review research into
novel treatments for childhood anxiety and depressive disorders designed to target …
and can persist despite the best available treatments. Here, we review research into
novel treatments for childhood anxiety and depressive disorders designed to target …
Cortical glutamate, Glx, and total N-acetylaspartate: potential biomarkers of repetitive transcranial magnetic stimulation treatment response and outcomes in major …
Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for
individuals with major depressive disorder (MDD) who have not improved with
standard therapies. However, only 30–45% of patients respond to rTMS. Predicting …
individuals with major depressive disorder (MDD) who have not improved with
standard therapies. However, only 30–45% of patients respond to rTMS. Predicting …
An automated platform for Assessing Working Memory and prefrontal circuit function
Working memory is a process for actively maintaining and updating task-relevant
information, despite interference from competing inputs, and is supported in part by
sustained activity in prefrontal cortical pyramidal neurons and coordinated …
information, despite interference from competing inputs, and is supported in part by
sustained activity in prefrontal cortical pyramidal neurons and coordinated …
Individual large-scale functional network mapping for major depressive disorder with electroconvulsive therapy
Personalized functional connectivity mapping has been demonstrated to be
promising in identifying underlying neurophysiological basis for brain disorders and
treatment effects. Electroconvulsive therapy (ECT) has been proved to be an effective …
promising in identifying underlying neurophysiological basis for brain disorders and
treatment effects. Electroconvulsive therapy (ECT) has been proved to be an effective …
Human-centred artificial intelligence for mobile health sensing: challenges and opportunities
Advances in wearable sensing and mobile computing have enabled the collection of
health and well-being data outside of traditional laboratory and hospital settings,
paving the way for a new era of mobile health. Meanwhile, artificial intelligence (AI) …
health and well-being data outside of traditional laboratory and hospital settings,
paving the way for a new era of mobile health. Meanwhile, artificial intelligence (AI) …