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User profiles for "Ana Costa"

Ana SH Costa

- Verified email at getmatterworks.com - Cited by 10901

Ana Costa

- Verified email at ineb.up.pt - Cited by 8501

Ana Carolina Oliveira Costa

- Verified email at ufsc.br - Cited by 5925

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

ET Chouchani, VR Pell, E Gaude, D Aksentijević… - Nature, 2014 - nature.com
Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then
restored, and underlies many disorders, notably heart attack and stroke. While reperfusion …

[PDF][PDF] Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages

EL Mills, B Kelly, A Logan, ASH Costa, M Varma… - Cell, 2016 - cell.com
Activated macrophages undergo metabolic reprogramming, which drives their pro-inflammatory
phenotype, but the mechanistic basis for this remains obscure. Here, we demonstrate …

Honey: Chemical composition, stability and authenticity

PM da Silva, C Gauche, LV Gonzaga, ACO Costa… - Food chemistry, 2016 - Elsevier
The aim of this review is to describe the chemical characteristics of compounds present in
honey, their stability when heated or stored for long periods of time and the parameters of …

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon… - Nature, 2018 - nature.com
The endogenous metabolite itaconate has recently emerged as a regulator of macrophage
function, but its precise mechanism of action remains poorly understood 1 , 2 , 3 . Here we …

[PDF][PDF] Fibroblast heterogeneity and immunosuppressive environment in human breast cancer

A Costa, Y Kieffer, A Scholer-Dahirel, F Pelon… - Cancer cell, 2018 - cell.com
Carcinoma-associated fibroblasts (CAF) are key players in the tumor microenvironment.
Here, we characterize four CAF subsets in breast cancer with distinct properties and levels of …

Work team trust and effectiveness

AC Costa - Personnel review, 2003 - emerald.com
This article aims to explore the nature and functioning of trust in work teams. Trust is defined
as a multi‐component variable with distinct but related dimensions. These include …

Critical review on biofilm methods

J Azeredo, NF Azevedo, R Briandet… - Critical reviews in …, 2017 - Taylor & Francis
Biofilms are widespread in nature and constitute an important strategy implemented by
microorganisms to survive in sometimes harsh environmental conditions. They can be beneficial …

[PDF][PDF] ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function

T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees… - Neuron, 2015 - cell.com
The mechanisms by which mutations in FUS and other RNA binding proteins cause ALS and
FTD remain controversial. We propose a model in which low-complexity (LC) domains of …

Trust within teams: The relation with performance effectiveness

AC Costa, RA Roe, T Taillieu - European journal of work and …, 2001 - Taylor & Francis
The acknowledgement that trust is important for the functioning of organizations has increased
the demand for research showing how this importance is reflected on the behaviour of its …

New insights into consumer-led food product development

AIA Costa, WMF Jongen - Trends in food science & technology, 2006 - Elsevier
This paper builds upon a review of relevant marketing, consumer science and innovation
management literature to introduce the concept of consumer-led new product development …

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