Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors EM McElnea, B Quill, NG Docherty, M Irnaten, WF Siah, AF Clark, ... Molecular vision 17, 1182, 2011 | 172 | 2011 |
The role of matricellular proteins in glaucoma DM Wallace, JE Murphy-Ullrich, JC Downs, CJ O'Brien Matrix Biology 37, 174-182, 2014 | 103 | 2014 |
The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo-and hetero-interacting abilities DM Wallace, AJ Lindsay, AG Hendrick, MW McCaffrey Biochemical and biophysical research communications 292 (4), 909-915, 2002 | 88 | 2002 |
Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells DME Wallace, AJ Lindsay, AG Hendrick, MW McCaffrey Biochemical and biophysical research communications 299 (5), 770-779, 2002 | 87 | 2002 |
Redox survival signalling in retina-derived 661W cells AM Mackey, N Sanvicens, G Groeger, F Doonan, D Wallace, TG Cotter Cell Death & Differentiation 15 (8), 1291-1303, 2008 | 74 | 2008 |
Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma J O’Callaghan, DE Crosbie, PS Cassidy, JM Sherwood, C Flügel-Koch, ... Human molecular genetics 26 (7), 1230-1246, 2017 | 72 | 2017 |
A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell JC O'Connor, DM Wallace, CJ O'Brien, TG Cotter Investigative ophthalmology & visual science 49 (10), 4237-4244, 2008 | 68 | 2008 |
Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells DM Wallace, AF Clark, KE Lipson, D Andrews, JK Crean, CJ O'Brien Investigative ophthalmology & visual science 54 (13), 7836-7848, 2013 | 63 | 2013 |
The role of lamina cribrosa cells in optic nerve head fibrosis in glaucoma DM Wallace, CJ O'Brien Experimental eye research 142, 102-109, 2016 | 59 | 2016 |
bFGF promotes photoreceptor cell survival in vitro by PKA‐mediated inactivation of glycogen synthase kinase 3β and CREB‐dependent Bcl‐2 up‐regulation C O’Driscoll, D Wallace, TG Cotter Journal of neurochemistry 103 (3), 860-870, 2007 | 54 | 2007 |
Hypoxia-induced changes in DNA methylation alter RASAL1 and TGFβ1 expression in human trabecular meshwork cells F McDonnell, M Irnaten, AF Clark, CJ O’Brien, DM Wallace PLoS One 11 (4), e0153354, 2016 | 46 | 2016 |
Histone deacetylase activity in conjunction with E2F‐1 and p53 regulates Apaf‐1 expression in 661W cells and the retina DM Wallace, TG Cotter Journal of neuroscience research 87 (4), 887-905, 2009 | 46 | 2009 |
Rosiglitazone acts as a neuroprotectant in retinal cells via up‐regulation of sestrin‐1 and SOD‐2 F Doonan, DM Wallace, C O’Driscoll, TG Cotter Journal of neurochemistry 109 (2), 631-643, 2009 | 43 | 2009 |
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina DM Wallace, M Donovan, TG Cotter Investigative ophthalmology & visual science 47 (7), 2765-2772, 2006 | 43 | 2006 |
Protein macroarray profiling of serum autoantibodies in pseudoexfoliation glaucoma EW Dervan, H Chen, SL Ho, N Brummel, J Schmid, D Toomey, ... Investigative ophthalmology & visual science 51 (6), 2968-2975, 2010 | 42 | 2010 |
The role of epigenetics in the fibrotic processes associated with glaucoma F McDonnell, C O’Brien, D Wallace Journal of ophthalmology 2014 (1), 750459, 2014 | 39 | 2014 |
IGF‐I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death AI Arroba, D Wallace, A Mackey, EJ De La Rosa, TG Cotter European Journal of Neuroscience 30 (6), 975-986, 2009 | 37 | 2009 |
Lysyl oxidase like 1: biological roles and regulation AG Greene, SB Eivers, EWJ Dervan, CJ O'Brien, DM Wallace Experimental eye research 193, 107975, 2020 | 33 | 2020 |
The role of lamina cribrosa tissue stiffness and fibrosis as fundamental biomechanical drivers of pathological glaucoma cupping AA Hopkins, R Murphy, M Irnaten, DM Wallace, B Quill, C O’Brien American Journal of Physiology-Cell Physiology, 2020 | 31 | 2020 |
The function of matricellular proteins in the lamina cribrosa and trabecular meshwork in glaucoma DM Wallace, O Pokrovskaya, CJ O'Brien Journal of Ocular Pharmacology and Therapeutics 31 (7), 386-395, 2015 | 30 | 2015 |