Thomas or Tom Duffy may refer to:
- Thomas Duffy (VC) (1805–1858), Irish recipient of the Victoria Cross in 1857
- Thomas A. Duffy (1906–1979), New York politician and judge
- Thomas C. Duffy (born 1955), American composer and conductor of the Yale University Concert Band
- Thomas J. Duffy, American designer/craftsman
- Thomas F. Duffy (born 1955), American actor
- Thomas T. Duffy (1835–?), American politician
- Tom Duffy (hurler), Irish hurler
- Tom Duffy (ringmaster), Irish circus performer and ringmaster
See also[edit]
- Thomas Gavan-Duffy (1867–1932), Irish trade unionist and politician