Protein-coding gene in the species Homo sapiens
Transcription factor 15 is a protein that in humans is encoded by the TCF15 gene .
[5]
Function [ edit ]
The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm . The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008].
References [ edit ]
Further reading [ edit ]
Guo P, Zhao KW, Dong XY, Sun X, Dong JT (2009). "Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells" . J. Biol. Chem . 284 (27): 18184–93. doi :10.1074/jbc.M109.007096 . PMC 2709394 . PMID 19419955 .
Coppiello G, Collantes M, Sirerol-Piquer MS, Vandenwijngaert S, Schoors S, Swinnen M, Vandersmissen I, Herijgers P, Topal B, van Loon J, Goffin J, Prósper F, Carmeliet P, García-Verdugo JM, Janssens S, Peñuelas I, Aranguren XL, Luttun A (2015). "Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake" . Circulation . 131 (9): 815–26. doi :10.1161/CIRCULATIONAHA.114.013721 . PMID 25561514 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .