He and She may refer to:

• He and She (album), by Wynton Marsalis
• He & She, American sitcom
• L'assoluto naturale, Italian film internationally released as He and She
• He and She (play), a 1920 play by Rachel Crothers

See also[edit]

• He-she, or shemale
• She/he, the gender-independent third person pronoun, in couplet form
• She and He (1963 film), a Japanese film
• She & Him, an American musical duo
• Him & Her, a British television show
• Her & Him, an adult film
• His and Hers (disambiguation)
• He, She and It, 1991 novel
• She (disambiguation)
• He (disambiguation)