CRAC might refer to:
- The CRAC-II "Calculation of Reactor Accident Consequences" study.
- A castle, as in Krak des Chevaliers.
- A Computer Room Air Conditioner.
- Clube Recreativo e Atlético Catalano, a Brazilian football (soccer) club commonly known as CRAC
- Clube Recreativo Atlético Campoverdense, a Brazilian football (soccer) club commonly known as CRAC
- Chinese Radio Amateurs Club, China Radio Association Amateur Radio Working Committee, Amateur Radio Club in China commonly known as CRAC
- Chisholm Residents Activity Club, a social club for residents of Chisholm College, which provides accommodation for students at La Trobe University
- Cholesterol recognition amino acid consensus sequence
- Crac, a 1981 Oscar-winning animated short film
- Calcium Release Activated Channels, ion channels in cell membrane
- Closed Reduction And Cast, an orthopaedic surgical procedure