THC Science

CHST5
Identifiers
Aliases	CHST5, I-GlcNAc-6-ST, I-GlcNAc6ST, glcNAc6ST-3, gn6st-3, hIGn6ST, carbohydrate sulfotransferase 5
External IDs	OMIM: 604817 HomoloGene: 69379 GeneCards: CHST5
Gene location (Human)
Chr.	Chromosome 16 (human)
End	75,536,108 bp
RNA expression pattern
	Top expressed in
	More reference expression data
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	23563
	n/a
	ENSG00000135702
	n/a
	Q9GZS9
	n/a
	NM_024533; NM_012126
	n/a
	NP_078809
	n/a
	Wikidata
View/Edit Human

Carbohydrate sulfotransferase 5 is an enzyme that in humans is encoded by the CHST5 gene.^[3]^[4]^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135702 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee JK, Bhakta S, Rosen SD, Hemmerich S (Sep 1999). "Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue". Biochemical and Biophysical Research Communications. 263 (2): 543–9. doi:10.1006/bbrc.1999.1324. PMID 10491328.
^ Akama TO, Nishida K, Nakayama J, Watanabe H, Ozaki K, Nakamura T, Dota A, Kawasaki S, Inoue Y, Maeda N, Yamamoto S, Fujiwara T, Thonar EJ, Shimomura Y, Kinoshita S, Tanigami A, Fukuda MN (Oct 2000). "Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene". Nature Genetics. 26 (2): 237–41. doi:10.1038/79987. PMID 11017086. S2CID 25547752.
^ "Entrez Gene: CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5".

External links[edit]

Human CHST5 genome location and CHST5 gene details page in the UCSC Genome Browser.

Further reading[edit]

Bernstein HB, Compans RW (Dec 1992). "Sulfation of the human immunodeficiency virus envelope glycoprotein". Journal of Virology. 66 (12): 6953–9. doi:10.1128/JVI.66.12.6953-6959.1992. PMC 240329. PMID 1433500.
Shilatifard A, Merkle RK, Helland DE, Welles JL, Haseltine WA, Cummings RD (Feb 1993). "Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine". Journal of Virology. 67 (2): 943–52. doi:10.1128/JVI.67.2.943-952.1993. PMC 237448. PMID 8419650.
Bartes A, Bhakta S, Hemmerich S (Apr 2001). "Sulfation of endothelial mucin by corneal keratan N-acetylglucosamine 6-O-sulfotransferase (GST-4beta)". Biochemical and Biophysical Research Communications. 282 (4): 928–33. doi:10.1006/bbrc.2001.4668. PMID 11352640.
Seko A, Nagata K, Yonezawa S, Yamashita K (Jun 2002). "Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma". Glycobiology. 12 (6): 379–88. doi:10.1093/glycob/12.6.379. PMID 12107080.
Akama TO, Misra AK, Hindsgaul O, Fukuda MN (Nov 2002). "Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate". The Journal of Biological Chemistry. 277 (45): 42505–13. doi:10.1074/jbc.M207412200. PMID 12218059.
Lee JK, Bistrup A, van Zante A, Rosen SD (Apr 2003). "Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications". Glycobiology. 13 (4): 245–54. doi:10.1093/glycob/cwg018. PMID 12626414.
de Graffenried CL, Bertozzi CR (Oct 2003). "Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis". The Journal of Biological Chemistry. 278 (41): 40282–95. doi:10.1074/jbc.M304928200. PMID 12855678.
Kitayama K, Hayashida Y, Nishida K, Akama TO (Oct 2007). "Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans". The Journal of Biological Chemistry. 282 (41): 30085–96. doi:10.1074/jbc.M703695200. PMID 17690104.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135702 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10491328-3] Lee JK, Bhakta S, Rosen SD, Hemmerich S (Sep 1999). "Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue". Biochemical and Biophysical Research Communications. 263 (2): 543–9. doi:10.1006/bbrc.1999.1324. PMID 10491328.

[pmid11017086-4] Akama TO, Nishida K, Nakayama J, Watanabe H, Ozaki K, Nakamura T, Dota A, Kawasaki S, Inoue Y, Maeda N, Yamamoto S, Fujiwara T, Thonar EJ, Shimomura Y, Kinoshita S, Tanigami A, Fukuda MN (Oct 2000). "Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene". Nature Genetics. 26 (2): 237–41. doi:10.1038/79987. PMID 11017086. S2CID 25547752.

[entrez-5] "Entrez Gene: CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5".

[1]

[2]

[3]

[4]

[5]

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