Protein-coding gene in the species Homo sapiens
Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene .[5] [6]
It is thought to act as a promoter of tumor development.[7]
Interactions [ edit ]
RAB25 has been shown to interact with RAB11FIP2 [8] [9] and RAB11FIP5 .[8] [9]
References [ edit ]
^ a b c GRCh38: Ensembl release 89: ENSG00000132698 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008601 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Pereira-Leal JB, Seabra MC (November 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol . 313 (4): 889–901. doi :10.1006/jmbi.2001.5072 . PMID 11697911 .
^ "Entrez Gene: RAB25 RAB25, member RAS oncogene family" .
^ Kessler, D; Gruen, GC; Heider, D; Morgner, J; Reis, H; Schmid, KW; Jendrossek, V (2012). "The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration" . Cellular Physiology and Biochemistry . 29 (5–6): 647–56. doi :10.1159/000295249 . PMID 22613965 .
^ a b Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins" . J. Biol. Chem . 276 (42): 39067–75. doi :10.1074/jbc.M104831200 . ISSN 0021-9258 . PMID 11495908 .
^ a b Prekeris, R; Davies J M; Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins" . J. Biol. Chem . 276 (42): 38966–70. doi :10.1074/jbc.M106133200 . ISSN 0021-9258 . PMID 11481332 .
Further reading [ edit ]
Goldenring JR, Shen KR, Vaughan HD, Modlin IM (1993). "Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung" . J. Biol. Chem . 268 (25): 18419–22. doi :10.1016/S0021-9258(17)46639-7 . PMID 8360141 .
Ray GS, Lee JR, Nwokeji K, et al. (1997). "Increased immunoreactivity for Rab11, a small GTP-binding protein, in low-grade dysplastic Barrett's epithelia". Lab. Invest . 77 (5): 503–11. PMID 9389793 .
Lapierre LA, Kumar R, Hales CM, et al. (2001). "Myosin vb is associated with plasma membrane recycling systems" . Mol. Biol. Cell . 12 (6): 1843–57. doi :10.1091/mbc.12.6.1843 . PMC 37346 . PMID 11408590 .
Prekeris R, Davies JM, Scheller RH (2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins" . J. Biol. Chem . 276 (42): 38966–70. doi :10.1074/jbc.M106133200 . PMID 11481332 .
Hales CM, Griner R, Hobdy-Henderson KC, et al. (2001). "Identification and characterization of a family of Rab11-interacting proteins" . J. Biol. Chem . 276 (42): 39067–75. doi :10.1074/jbc.M104831200 . PMID 11495908 .
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs" . Genome Res . 11 (10): 1758–65. doi :10.1101/gr.180101 . PMC 311163 . PMID 11591653 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science . 307 (5715): 1621–5. Bibcode :2005Sci...307.1621B . doi :10.1126/science.1105776 . PMID 15761153 . S2CID 39457788 .
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 . PMID 17353931 .
Fan Y, Xin XY, Chen BL, Ma X (2007). "Knockdown of RAB25 expression by RNAi inhibits growth of human epithelial ovarian cancer cells in vitro and in vivo". Pathology . 38 (6): 561–7. doi :10.1080/00313020601024037 . PMID 17393986 . S2CID 85960469 .